肺心病患者血清甲状腺素含量变化及其临床意义

目的探讨75例无甲状腺疾病的肺心病患者血清三碘甲状腺原氨酸(T3)、血清甲状腺素(T4)和血清促甲状腺激素(TSH)的含量变化及其关系.方法检测75例肺心病患者血清T3、T4和TSH含量,另选80例健康体检者作为正常对照组.结果肺心病患者血清T3降低,与正常对照组比较,P＜0.01,血清T4与正常对照组比较P＞0.05.有肺性脑病、消化道出血严重并发症时,低T3血症尤为显著,P＜0.01.且多伴有低T4血症,P＜0.05.血清T4血症越低,病死率越高.结论血清T3、T4含量可作为判断肺心病轻重和预后指标之一.

SERUM LEVELS OF THYROXINE IN PATIENTS WITH COR PULMONALE

Objective To investigate blood levels of T 3,T 4,TSH in cor pulmonale patients and the correlation among them. Methods Blood levels of T 3,T 4,TSH in 75 patients with cor pulmonale were detected,which were compared with those of normal 80 healthy adults in our laboratory. Results The blood levels of T 3 in cor pulmonale patients were significantly lower than those of controls(P<0.01). T 3 level was the lowest when companied with side effects such as pulmo-cerebral syndrome,gastrointestinal hemorrhage(P<0.01), and blood levels of T 4 were lower either(P<0.05). Conclusion Blood levels of T 3,T 4 may be clinical indexes for determining degree and prognosis of cor pulmonale patients.