浙江省湖州市自然人群乙型病毒性肝炎的流行特征

目的 了解浙江省湖州市自然人群乙型病毒性肝炎(乙肝)病毒(HBV)感染情况与流行病学特征.方法 在湖州市按农村山区、农村平原水乡、城镇,随机抽取1666名健康人为研究对象,用酶联免疫吸附试验检测血清乙肝病毒表面抗原、乙肝病毒表面抗体、乙肝病毒核心抗体、乙肝病毒e抗原、乙肝病毒e抗体.结果 湖州市自然人群HBV标化流行率为36.47%,乙肝流行率＜10岁组儿童最低,为4.93%;HBsAg携带率为4.14%,10岁以下携带率为0;低于全国和全省人群乙肝流行率.结论 湖州市乙肝流行率已从高流行区进入中流行区,乙肝疫苗接种效果明显.

Epidemiological characteristics of viral hepatitis B in natural population in Huzhou city, Zhejiang province

Objective The study was conducted to investigate the conditions of hepatitis B virus (HBV) infection in Huzhou city, Zhejiang province and its epidemiological characteristics. Methods A total of 1666 randomly selected healthy subjects from the rural mountain areas, plains and regions of rivers and lakes, and towns in Huzhou city participated in the study. Their serum hepatitis B virus surface antigen (HBsAg), hepatitis B virus surface antibody , hepatitis B virus core antibody, hepatitis B virus e antigen. and hepatitis B virus e antibody levels were measured using the enzyme-linked immunosorbent assay. Results The standardized prevalence rate of HBV infection in natural population in Huzhou city was 36.47%, The lowest prevalence rate of hepatitis B was found in the<10-year-old group of children, being 4.93%; the HBsAg carrier rate was 4.14%, whereas this rate was 0 in 10-year-olds. The HBV prevalence rate was lower than the national and provincial rates. Conclusion Huzhou has become a moderately prevalent area from a previously highly prevalent one due to the hepatitis B prevalence rate shown in the study. It was revealed that the hepatitis B vaccination had evident effects.