Hepatitis E Virus seroprevalence and chronic infections in patients with HIV, Switzerland |
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| Authors: | Kenfak-Foguena Alain,Schöni-Affolter Franziska,Bürgisser Phillippe,Witteck Andrea,Darling Katharine E A,Kovari Helen,Kaiser Laurent,Evison John-Marc,Elzi Luigia,Gurter-De La Fuente Vanina,Jost Josef,Moradpour Darius,Abravanel Florence,Izpopet Jacques,Cavassini Matthais Data Center of the Swiss HIV Cohort Study, Lausanne, Switzerland |
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| Affiliation: | Centre Hospitalier Universitaire Vaudois and Lausanne University, Lausanne, Switzerland. |
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| Abstract: | We screened 735 HIV-infected patients in Switzerland with unexplained alanine aminotransferase elevation for hepatitis E virus (HEV) immunoglobulin G. Although HEV seroprevalence in this population is low (2.6%), HEV RNA can persist in patients with low CD4 cell counts. Findings suggest chronic HEV infection should be considered as a cause of persistent alanine aminotransferase elevation. |
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| Keywords: | viruses HIV hepatitis HEV Switzerland ALT elevation alanine transaminase liver enzymes chronic infection dispatch |
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