| 人工胃液对五味子甲素的溶出率考察 |
| |
| 引用本文： | 常明泉,杨光义,常晨,黄良永.人工胃液对五味子甲素的溶出率考察[J].中国药师,2014(11):1837-1839. |
| |
| 作者姓名： | 常明泉 杨光义 常晨 黄良永 |
| |
| 作者单位： | 湖北医药学院附属太和医院药学部 湖北十堰 442000；;湖北医药学院附属太和医院药学部 湖北十堰 442000；;江南大学化学与材料工程学院2011级学生;湖北医药学院附属太和医院药学部 |
| |
| 基金项目： | 太和科研基金资助项目（编号:2013JJXM021）; 湖北省重大科学技术鉴定成果（登记号：EK2012D 150018000359） |
| |
| 摘 要： | 目的：考察人工胃液对五味子甲素溶出率的影响,为五味子优选最佳提取方法提供参数。方法：用人工胃液提取五味子,用水提取法做对照,用高效液相色谱法测定提取物中的五味子甲素,比较两种溶剂对五味子甲素的溶出率。结果：60min时人工胃液提取溶出率为0.483%,水提法溶出率为0.362%。结论：人工胃液对五味子甲素的溶出率比水提取法高33.4%,能显著提高五味子甲素的溶出率。
|
| 关 键 词： | 五味子 人工胃液 溶出率 五味子甲素 |
| 收稿时间： | 2014/4/19 0:00:00 |
| 修稿时间： | 7/6/2014 12:00:00 AM |
Effect of Artificial Gastric Juice on Dissolution of Schizandrin A |
| |
| Chang Mingquan,Yang Gaungyi,Chang Chen and Huang Liangyong.Effect of Artificial Gastric Juice on Dissolution of Schizandrin A[J].China Pharmacist,2014(11):1837-1839. |
| |
| Authors: | Chang Mingquan Yang Gaungyi Chang Chen and Huang Liangyong |
| |
| Institution: | Chang Mingquan, Yang Gaungyi, Chang Chen, Huang Liangyong(1. Taihe Hospital Affiliated to Hubei University of. Medicine,Hubei Shiyan 442000, China; 2. Grade 2011 Undergraduate Student of Jiangnan University Chemical and Material Engineering College ) |
| |
| Abstract: | Objective：To study the effect of artificial gastric juice on the dissolution of schizandrin A to provide the parameters for the best extraction method of Schisandra chinensis. Methods：Schisandra chinensis was respectively extracted by artificial gastric juice and water. Schizandrin A in the extracts was determined by HPLC, and the dissolution of schizandrin A in artificial gastric juice and water was studied and compared. Results：At 60 min, schizandrin A dissolution was 0. 483% in artificial gastric juice, and 0. 362%in water. Conclusion：The dissolution of schizandrin A in artificial gastric juice is 33. 4% higher than that in water, suggesting artificial gastric juice can significantly improve the dissolution of schisandrin A. |
| |
| Keywords: | Schisandra chinensis Artificial gastric juice Dissolution Schizandrin A |
| 本文献已被 维普 等数据库收录！ |
| 点击此处可从《中国药师》浏览原始摘要信息 |
| 点击此处可从《中国药师》下载免费的PDF全文 |
