GC法测定甘油止痒洗剂中苯酚和薄荷脑的含量

目的：建立GC法测定甘油止痒洗剂中苯酚和薄荷脑的含量方法。方法：色谱柱为Zebron ZB-Wax（0.32 mm×30.0 m,0.50μm）毛细管柱色谱柱;FID检测器;柱温为60℃,保持1 min,然后以8℃·min^-1速率升温至160℃,保温10 min,进样口温度180℃,检测器温度300℃。载气为氮气。结果：苯酚和薄荷脑的线性范围分别是0.5-10.0 mg·ml^-1（r=0.999 9）和0.25-5.0 mg·ml^-1（r=0.999 9）。苯酚和薄荷脑的平均回收率分别为99.01%（RSD=0.90%,n=9）和99.70%（RSD=0.98%,n=9）。结论：该方法简单,结果准确可靠,可用于止痒洗剂中苯酚和薄荷脑的含量测定。

Determination of Phenol and L Menthol in Glycerin Zhiyang Lotions by GC

Objective：To establish a GC method for the determination of phenol and L-menthol in glycerin Zhiyang lotions. Methods：A Zebron ZB-WAX（0. 32 mm × 30. 0 m,0. 50 μm） capillary column was used with an FID detector. The column temperature was 60℃, maintained for 1 min, and then raised to 160℃ at the rate of 8℃·min-1 , and maintained 10 minutes. The inlet temperature was 180℃, the detector temperature was 300℃, and the carrier gas was nitrogen. Results：The linear range of phenol and L-menthol was 0. 5-10. 0 mg·ml-1（r=0. 999 9） and 0. 25-5. 0 mg·ml-1（r=0. 999 9）, respectively. The average recovery of phenol and L-menthol was 99. 01%（RSD=0. 90%,n=9）and 99. 70%（RSD=0. 98%,n=9）, respectively. Conclusion： The method is simple, accurate and reliable, and can be used to determine the concentration of phenol and L-menthol in glycerin Zhiyang lotions.