| 心脏移植术后的骨质疏松症 |
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| 引用本文： | 李裕明,M.J.Seibel,C.Kasperk,R.Ziegler. 心脏移植术后的骨质疏松症[J]. 中华器官移植杂志, 1999, 20(1): 56-58 |
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| 作者姓名： | 李裕明 M.J.Seibel C.Kasperk R.Ziegler |
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| 作者单位： | 1. 同济医科大学附属协和医院,武汉,430022
2. 德国海德堡大学医学院内科医院 |
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| 摘 要： | 目的 研究心脏移植后患者的骨质疏松症的发病情况。方法 采用双能Ｘ线吸收扫描仪（ＤＸＡ）测定５３例心脏移植患者和２２例准备接受心脏移植患者的腰椎和股肌骨颈的骨矿密度（ＢＭＩ）。
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| 关 键 词： | 心脏移植 骨质疏松 肾上腺皮质激素 环孢素A |
Osteoporosis after cardiac transplantation |
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| LI Yuming,M.J.Seibel,C.Kasperk,R.Ziegler. Osteoporosis after cardiac transplantation[J]. Chinese Journal of Organ Transplantation, 1999, 20(1): 56-58 |
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| Authors: | LI Yuming M.J.Seibel C.Kasperk R.Ziegler |
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| Abstract: | Objective To study the prevalence of osteoporosis in patients undergoing cardiac transplantation.Methods By using dual energy X ray absorptiometry, bone mineral density(BMD) in lumbar spine and femoral neck was measured in 53 adult patients after cardiac transplantation and 22 patients prior to heart transplantation.Results Mean BMD in lumbar spine and femoral neck was roughly one standard deviation below the mean for age matched and sex matched subjects both for men and women. Eight patients( 15.1% ) had densitometric evidence of osteopenia defined as a Z score of - 2.0 SD or less. The mean BMD in lumbar spine and femoral neck was normal in 22 patients without undergoing cardiac transplantation. The most rapid drop in vertebral BMD occurred during the first 2 years following cardiac transplantation.Conclusion Osteopenia are common in the patients after cardiac transplantation, which might be related to the immunosuppressive therapy-glucocorticoid and cyclosporine A. |
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| Keywords: | Heart/transplantation Osteoporosis Adrenal cortex hormones Cyclosporins |
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