| 一氧化氮和一氧化氮合酶在鼠脑内形成吗啡依赖的作用研究 |
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| 引用本文： | 李国海,叶静,黄明生,王英成.一氧化氮和一氧化氮合酶在鼠脑内形成吗啡依赖的作用研究[J].四川精神卫生,2001,14(3):142-143. |
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| 作者姓名： | 李国海 叶静 黄明生 王英成 |
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| 作者单位： | 华西医科大学附一院心理卫生研究所, |
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| 摘 要： | 目的：研究一氧化氮（NO）和一氧化氮合酶（NOS）在吗啡依赖形成中的作用。方法；对吗啡依赖和戒断大鼠脑内NO含量和NOS活力进行测定。结果：未发现吗啡依赖和戒断大鼠脑内NO含量和NOS活力有改变。结论：对NO／NOS与吗啡依赖的关系还有待进一步研究。
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| 关 键 词： | 吗啡依赖 一氧化氮 一氧化氮合酶 |
| 修稿时间： | 2000年10月12 |
A study on nitric oxide and nitric oxide synthase in the brains from morphine dependentrats |
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| LI Guohai,YE Ging,HUANG Mingsheng,et al..A study on nitric oxide and nitric oxide synthase in the brains from morphine dependentrats[J].Sichuan Mental Health,2001,14(3):142-143. |
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| Authors: | LI Guohai YE Ging HUANG Mingsheng |
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| Institution: | LI Guohai,YE Ging,HUANG Mingsheng,et al.An Institute of Mental H ealth,The First Affiliated Hospital of West China University of Medical Sciences .610041 |
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| Abstract: | Objective To study the role of nitr ic oxide(NO) and nitric oxide synthase(NOS) in the development of morphine depende nce.Methods The level of nitric oxide and the activity of nitric oxide synthase were measured in morphine-dependent and morphine-wi thdrawn rats.Results No significant changes in the NO lev el and the NOS activity were found.Conclusion The correlation between NO/NOS and morphine dependence remains to be studied. |
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| Keywords: | Morphine Nitric oxide Nitric oxide synthase |
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