Two different glomerular diseases in the same patient at an interval of 7 years. |
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| Authors: | Giovanni M Frascà Letizia Soverini Paola Preda Gianandrea Pasquinelli Claudio Orsi Rita Prandini Alba Vangelista Sergio Stefoni |
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| Institution: | Nephrology, Dialysis and Renal Transplantation Unit, Pathology Department, St Orsola University Hospital, Bologna, Italy. frasca@orsola-malpighi.med.unibo.it |
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| Abstract: | |
Introduction
| Overlapping of different glomerulopathies has already been observedin renal biopsies from diabetic as well as non-diabetic patients1]. Unlike other reports, the present paper describes a patientwhere two distinct forms of immunological glomerulonephritiswith a different histological and clinical picture occurredseparately at some years’ interval from each other. Thisfinding suggests an individual susceptibility of the patientto immunological renal injury and gives food for speculationon the pathogenesis of glomerulonephritis.
Case
| The patient here described was born in Southern Italy in 1966.Family investigation proved negative for glomerular diseases,renal failure, arterial hypertension and diabetes mellitus.In 1991, when he was 25 years old, he had an episode of macroscopichaematuria during an upper airways infection, and this recurredin November 1994, at the age of 28. At that time, urinalysisrevealed haematuria
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| Keywords: | double glomerulopathy IgA nephritis membranous glomerulonephritis |
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