Pediatric liver transplantation in Hong Kong—a domain with scarce deceased donors |
| |
Authors: | Kwong Leung Chan Sheung Tat Fan Chung Mau Lo William I Wei Raymond Wai Man Ng Ho Yu Chung Kelvin Kwok Chai Ng See Ching Chan Kwok Wah Chan Wai Kuen Tso Nai Shun Tsoi Paul Kwong Hang Tam John Wong |
| |
Institution: | aDepartment of Surgery, The University of Hong Kong, Hong Kong, China;bDepartment of Pathology, The University of Hong Kong, Hong Kong, China;cDepartment of Radiology, The University of Hong Kong, Hong Kong, China;dDepartment of Paediatrics, The University of Hong Kong, Hong Kong, China |
| |
Abstract: | AimThe study aimed to assess the outcome of live-donor liver transplantation for pediatric patients in a region with limited access to deceased donors.Patients and MethodsFrom September 1993 to September 2008, 78 pediatric patients aged between 73 days and 17 years (mean, 40 months) received 83 liver transplants. Sixty-two were living-related liver transplantations (LRLTs), and 21 were deceased-donor liver transplantations (DDLTs). The mean follow-up period was 6.5 years. The prospectively collected data of these patients were analyzed retrospectively.ResultsThe 1-, 2-, and 5-year survival rates of patients and grafts were 91%, 90%, 88% and 87%, 86%, 83%, respectively. The survival rates of LRLT patients and DDLT patients were 89%, 89%, 87%, and 90%, 86%, 86%, respectively (P = .58). The survival rates of patients aged 12 months or younger and patients older than 12 months were 95%, 92%, 90% and 90%, 90%, 87%, respectively (P = .65). One live donor developed temporary peroneal palsy, and another developed lung collapse (3%, 2/62). All live donors resumed their normal activities with no difficulty.ConclusionWith meticulous surgical techniques and postoperative care, it is justifiable to accept donated livers from voluntary live donors for transplantation to save pediatric patients in a place with scarce deceased donors. |
| |
Keywords: | Pediatric liver transplantation Scarce deceased donors |
本文献已被 ScienceDirect 等数据库收录! |
|