兔坐骨神经实验性电损伤后的功能评价

目的 观察兔坐骨神经实验性电损伤后不同时期神经电特性的改变，并了解其变化规律。方法 以不同的电压损伤神经后按不同时间进行功能指标观察。包括神经传导速度、潜伏期、动作电位峰值、刺激阈值。结果 动作电位峰值随着损伤电位的增加而减少，随着时间的延长逐渐恢复，潜伏期随着损伤电压的增大而增大，随着时间的延长逐渐恢复正常，随着损伤电压增大传导速度逐渐降低，随着观察时间的延长传导速度逐渐恢复。结论 神经损伤的程度与损伤电压直接相关，神经纤维的粗细影响着神经受损的程度。动作电位峰值可以反映出神经干的损伤程度和神经纤维的再生情况。

Evaluation of sciatic nerve functions following electrical injury in rabbits

AIM The sciatic nerve of rabbit was injured by electrical current experimentally and the eletrophysiological indexes of the nerve were measured for the study of the injury mechanism. METHODS The sciatic nerve was injured with different electrical current and in different observation period the nerve conduction velocity, action potential peak value, latent period, stimulative threshold were measured. RESULTS The nerve conduction velocity and action potential peak value decreased along with augmentation of the injury current. Nevertheless, the latent period and stimulative threshold were the opposite. CONCLUSION The injury degree of the nerve correlates with the magnitude of the injury current. The thickness of the nerve affects the nerve injured extent. The action potential peak value can reflect the regeneration of the nerve fibers.