| 鼻咽癌常规和超分割后加速放疗的疗效分析 |
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| 引用本文： | 何霞云,郭小毛,章真,叶明,潘自强,何少琴,刘泰福. 鼻咽癌常规和超分割后加速放疗的疗效分析[J]. 中华放射医学与防护杂志, 2013, 33(4): 392-395 |
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| 作者姓名： | 何霞云 郭小毛 章真 叶明 潘自强 何少琴 刘泰福 |
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| 作者单位： | 200032 上海, 复旦大学附属肿瘤医院放疗科 复旦大学上海医学院肿瘤学系;200032 上海, 复旦大学附属肿瘤医院放疗科 复旦大学上海医学院肿瘤学系;200032 上海, 复旦大学附属肿瘤医院放疗科 复旦大学上海医学院肿瘤学系;200032 上海, 复旦大学附属肿瘤医院放疗科 复旦大学上海医学院肿瘤学系;200032 上海, 复旦大学附属肿瘤医院放疗科 复旦大学上海医学院肿瘤学系;200032 上海, 复旦大学附属肿瘤医院放疗科 复旦大学上海医学院肿瘤学系;200032 上海, 复旦大学附属肿瘤医院放疗科 复旦大学上海医学院肿瘤学系 |
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| 摘 要： | 目的 比较鼻咽癌常规和超分割后加速放疗的局部控制率和生存率。 方法 200例初治鼻咽癌患者根据计算机产生的随机数入常规组和超分割后加速放疗组,鼻咽原发灶采用60Co γ射线或6 MV X射线外照射,常规组70 Gy/35次/7周,超分割后加速放疗组前4周采用超分割1.2 Gy/次,剂量为48 Gy/40次,后2周加速超分割1.5 Gy/次,剂量为30 Gy/20次,均为2次/d,间隔≥6 h,5 d/周。结果 常规组99例中,远处转移25例、鼻咽复发25例、颈部复发16例;超分割后加速放疗组101例中,远处转移18例、鼻咽复发16例、颈部复发13例。常规组和超分割后加速组5年鼻咽局部控制率分别为75.9%、87.6% (χ2=4.066, P<0.05),总生存率分别为58.0%、74.1%(χ2=5.076, P<0.05),5年无远处转移率分别为74.1%、83.3%(P> 0.05),颈部局部控制率分别为81.5%、90.0%(P> 0.05)。结论 与常规分割相比,超分割后加速放疗组提高了鼻咽局部控制率和总生存率,未减少颈部复发和远处转移率。
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| 关 键 词： | 鼻咽肿瘤 常规分割 超分割后加速放疗 局部控制率 |
| 收稿时间： | 2012-07-24 |
Efficacy of conventional radiotherapy and late course accelerated hyperfractionationated radiotherapy for nasopharyngeal carcinoma |
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| HE Xia-yun,GUO Xiao-mao,ZHANG Zhen,YE Ming,PAN Zi-qiang,HE Shao-qin and LIU Tai-fu. Efficacy of conventional radiotherapy and late course accelerated hyperfractionationated radiotherapy for nasopharyngeal carcinoma [J]. Chinese Journal of Radiological Medicine and Protection, 2013, 33(4): 392-395 |
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| Authors: | HE Xia-yun GUO Xiao-mao ZHANG Zhen YE Ming PAN Zi-qiang HE Shao-qin LIU Tai-fu |
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| Affiliation: | Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China;Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China;Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China;Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China;Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China;Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China;Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China |
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| Abstract: | |
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| Keywords: | Nasopharyngeal carcinoma Conventional radiotherapy Late course accelerated hyperfractionated radiotherapy Control rate |
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