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Epileptic syndromes in childhood and adolescence
Authors:Colin D Ferrie
Institution:1. University of Catanzaro, School of Medicine, Department of Science of Health, Catanzaro, Italy;2. National Council of Research (CNR), Institute of Neurological Science, Catanzaro, Italy;1. Child Neuropsychiatric Unit, Neuroscience Department, University of Parma, Italy;2. Department of Information Engineering, University of Parma, Italy;1. Pediatric Neurology Unit, Hadassah Hebrew University Hospital, Jerusalem, Israel;2. Dana-Dwek Children''s Hospital, Tel Aviv University, Tel Aviv, Israel;1. Department of Neurology, Barrow Neurological Institute, Phoenix, Arizona;2. Division of Pediatric Neurology, Barrow Neurological Institute at Phoenix Children''s Hospital, Phoenix, Arizona;3. Division of Pediatric Neurology, Johns Hopkins Hospital, Baltimore, Maryland;4. Department of Neurology, University of Oklahoma, Oklahoma City, Oklahoma
Abstract:The syndromic approach to the diagnosis of epilepsy has been one of the most significant advances in clinical epileptology in the past few decades. An epilepsy syndrome is defined by the clustering of signs and symptoms, including investigational results, which define a unique epilepsy condition. There is no completely satisfactory way of grouping the very large number of epilepsy syndromes that occur in childhood and adolescence. In this paper the following are reviewed: the idiopathic epilepsy syndromes in infancy; the idiopathic focal epilepsies of childhood and the familial (autosomal dominant) focal epilepsies; the idiopathic generalised epilepsies; the symptomatic and probably symptomatic focal epilepsies; and the epileptic encephalopathies. Although a syndrome diagnosis is not possible in all children with epilepsy, where it is, it is likely to offer the best guide to management and prognosis.
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