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Synchronous occurrence of colonic intraepithelial neoplasia and small bowel stromal tumour
Authors:Sami Karoui  Afef Ouaz  Wael Rebai  Nadia Boujelbane  Fadhel Fteriche  Kais Nouira  Meriem Serghini  Lamia Kallel  Jalel Boubaker  Slim Haouet  Emna Mnif  Faouzi Chebbi  Zoubeir Ben Safta  Azza Filali
Affiliation:1. Department of Gastroenterology A, La Rabta Hospital, Tunis 1007, Tunisia;2. Department of Surgery, La Rabta Hospital, Tunis 1007, Tunisia;3. Department of Pathology, La Rabta Hospital, Tunis 1007, Tunisia;4. Department of Radiology, La Rabta Hospital, Tunis 1007, Tunisia;1. Hepatology Department, Hôpital Pitié-Salpêtrière, Assistance Publique–Hôpitaux de Paris, 47-83, boulevard de l’Hôpital, 75651 Paris cedex 13, France;2. UMR_S 938, INSERM, Université Pierre et Marie Curie, Université Paris 06, Institute of Cardiometabolism and Nutrition (ICAN), Centre de Recherche Saint-Antoine & Paris, France;3. BioPredictive, Paris, France;4. Biochemistry Department, Hôpital Pitié-Salpêtrière, Assistance Publique–Hôpitaux de Paris, Paris, France;5. Hepatology, Hôpital Haut Leveque, Bordeaux, France;1. Edouard Herriot Hospital – HCL, Department of Digestive Diseases, Claude Bernard Lyon 1 University, Lyon, France;2. Jean Mermoz Hospital, Lyon, France;3. Archet II Hospital, Department of Digestive Diseases, Nice, France;4. Avignon Hospital, Department of Digestive Diseases, Avignon, France;5. Conception Hospital – AP-HM, Department of Digestive Diseases, Marseille, France;6. Ibn Sina Hospital, Department of Digestive Diseases, Rabat, Morocco;7. Lyon Sud Hospital, Department of Digestive Diseases, Pierre Benite, France;8. Saint Philibert Hospital, Department of Digestive Diseases, Lomme, France;9. Cochin Hospital – AP-HP, Department of Digestive Endoscopy, Paris, France;10. Société Française d’Endoscopie Digestive, Paris, France;1. Department of Digestive Diseases, Hospices Civils de Lyon, Edouard Herriot Hospital, France;2. Claude Bernard Lyon 1 University, Lyon, France;1. Department of Ophthalmology, University Hospital, CHU Grenoble, Grenoble, France;2. INSERM U1042, Hypoxia and Physiopathology Laboratory, Joseph Fourier University, Grenoble, France;1. Division of Urological Surgery and Center for Surgery and Public Health, Brigham and Women''s Hospital, Harvard Medical School, Boston, MA 02120, USA;1. Department of Medical Informatics, Henri Mondor Hospital, Assistance Publique Hôpitaux de Paris, 51 av. Du Mal de Lattre, 94010 Creteil, France;2. Faculty of Medicine, University Paris-Est, 8, rue du Général Sarrail, 94010 Creteil, France
Abstract:We report the diagnosis of synchronous gastrointestinal stromal tumours affecting the small bowel and intraepithelial neoplasia of the colon in a 52-year-old patient. After surgical resection of the two tumours outcome was favourable. We discuss the causality of this association, based on a literature review of the few previously published cases.
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