磁共振弥散加权成像在一氧化碳中毒迟发性脑病诊断中应用研究

目的:探讨磁共振弥散加权成像诊断一氧化碳中毒迟发性脑病的应用价值。方法:回顾性分析2017年5月~2018年10月本院诊治的36例一氧化碳中毒迟发性脑病患者(观察组)及36例单纯一氧化碳中毒患者(对照组)的病例资料,所有患者均行磁共振弥散加权成像检查,比较两组影像学表现及双侧大脑皮层半卵圆中心表现弥散系数(ADC)值。结果:观察组患者各时间段ADC均值均低于对照组,差异有统计学意义(P<0.05);MR影像学表现中一氧化碳中毒患者两侧大脑皮层、苍白球及皮层下区T1WI呈等信号,T2WI呈高信号,同时所有异常信号均出现两侧对称性改变;一氧化碳中毒迟发性脑病患者MR影像学表现为脑实质伴有异常信号灶,主要以基底节区病变为主,且呈稍长T1、T2信号,DWI序列检查,部分患者病变区信号偏高。结论:磁共振弥散加权成像在一氧化碳中毒迟发性脑病患者诊断中具有较高的临床应用价值,其可通过DWI判断病情,且能够与单纯一氧化碳中毒患者进行有效区分。

Application of Magnetic Resonance Diffusion Weighted Imaging in the Diagnosis of Delayed Encephalopathy Caused by Carbon Monoxide Poisoning

Objective: To investigate the value of diffusion-weighted imaging in the diagnosis of delayed encephalopathy caused by carbon monoxide poisoning. Methods: A retrospective analysis of 36 cases of patients with delayed encephalopathy caused by carbon monoxide poisoning(observation group) and 36 patients with simple carbon monoxide poisoning(control group) from May 2017 to October 2018 was performed. All patients were magnetic. Resonance diffusion-weighted imaging was performed to compare the imaging findings of the two groups and the diffusion coefficient(ADC) values of the bilateral cerebral cortex semi-oval centers. Results: The mean ADC values of the observation group were lower than those of the control group(P<0.05). In the MR imaging findings, the cerebral cortex, globus pallidus and subcortical region of the patients with carbon monoxide poisoning showed equal signals. T2WI showed a high signal, and all abnormal signals showed bilateral symmetry changes. MR imaging of patients with delayed encephalopathy caused by carbon monoxide poisoning showed brain parenchyma with abnormal signal lesions, mainly basal ganglia lesions, and slightly longer. T1, T2 signals, DWI sequence examination, some patients with high lesions in the lesion area. Conclusion: Magnetic resonance diffusion-weighted imaging has a high clinical value in the diagnosis of patients with delayed encephalopathy caused by carbon monoxide poisoning. It can be judged by DWI and can be effectively distinguished from patients with carbon monoxide poisoning alone.