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200只比格犬心电图分析
引用本文:刘启德,许庆文,杨守凯,符坚,王宁生.200只比格犬心电图分析[J].中国药理学与毒理学杂志,2002,16(3):231-234.
作者姓名:刘启德  许庆文  杨守凯  符坚  王宁生
作者单位:1. 广州中医药大学国家新药,中药,安全评价研究重点实验室,广东,广州,510405
2. 广东省顺德实验动物研究所,广东,顺德,528300
摘    要:目的 对不同年龄的比格 (Beagle)犬 ,进行了6个导联的心电图描记和分析 ,建立了心电图基本数据。方法  2 0 0条 6~ 36月龄Beagle犬 ,在清醒情况下记录Ⅰ、Ⅱ、Ⅲ、aVR、aVL和aAF 6个导联的心电图。结果  2 0 0只Beagle犬均为窦性心律。不同性别和年龄的犬心率不同 ,雌性犬略快 ,随年龄增加 ,心率变缓。Beagle犬心电图各波形与人相似 ,P R间期为 0 .0 9~ 0 .12s ,QRS波群为 0 .0 4~ 0 .0 6s ,Q T间期为 0 .17~ 0 .2 1s。随着年龄增大 ,P R间期和Q T间期延长 ,QRS波群年龄性别差异不显著。S T段一般与QRS末端合并 ,大多数位于等电位线 ,S T段上移的占 12 % ,一般为上抬或斜升型下降 ,但一般不超过 1mm。Beagle犬存在着窦性心律不齐 ,比例为 15 %。结论 建立了心电图基本数据 ,可供实验时参考

关 键 词:  Beagle  心电图描记术
收稿时间:2001-11-26

Analysis of electrocardiogram in 200 beagle dogs

LIU Qi-De, XU Qing-Wen, YANG Shou-Kai, FU Jian, WANG Ning-Sheng

.Analysis of electrocardiogram in 200 beagle dogs[J].Chinese Journal of Pharmacology and Toxicology,2002,16(3):231-234.
Authors:

LIU Qi-De  XU Qing-Wen  YANG Shou-Kai  FU Jian  WANG Ning-Sheng

Institution:

LIU Qi-De1, XU Qing-Wen1, YANG Shou-Kai2, FU Jian2, WANG Ning-Sheng1

Abstract:AIM In order to establish the electrocardiogram(ECG) database in beagle dog. METHODS ECG were examined in 200 dogs between 6 to 36 months old. Electrocardiogram of six leads including Ⅰ, Ⅱ, Ⅲ, aVR, aVL and aAF was recorded in a conscious state. RESULTS ]All dogs had a sinus rhythm. The heart rate was related to sex and age, slower in female and faster in younger. The shape of dog ECG was similar to that of human, P-R interval was 0.09-0.12 s, QRS complex 0.04-0.06 s and Q- T interval was 0.12-0.21 s. P-R and Q- T intervals were lengthened with age, but QRS showed no correlation with ages and sex. ST segment was blended with the terminal of QRS complex, and mostly located at the iso-electric level, but 12% of ST segment shifted straightly upward or slanted down, not exceeding 1 mm. Sinus arrhythmia appeared in 15% of beagle dogs. CONCLUSION The basic date of ECG of beagle dogs are provided to be a reference in related experiments.
Keywords:Dogs  beagle  electrocardiography
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