| 髓系肉瘤的临床特征和生存分析 |
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| 引用本文： | 高如攀,邹善华,李锋,王伟光,程志祥,袁玲,程韵枫.髓系肉瘤的临床特征和生存分析[J].肿瘤防治研究,2013,40(6):538-540. |
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| 作者姓名： | 高如攀 邹善华 李锋 王伟光 程志祥 袁玲 程韵枫 |
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| 作者单位： | 200032 上海，复旦大学附属中山医院血液科 |
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| 摘 要： | 目的探讨髓系肉瘤（myeloid sarcoma,MS)患者的临床特征、治疗方法和预后。方法回顾性分析17例髓系肉瘤患者的临床特征和治疗方法，应用Kaplan-Meier法行生存分析。结果17例髓系肉瘤的发生部位包括淋巴结、乳腺、宫颈、眼眶等。孤立性髓系肉瘤8例，白血病性髓系肉瘤9例。MS的1年和3年总生存率为（72.0±12.0）%、（45.7±14.4）%。孤立性和白血病性髓系肉瘤3年生存率分别为（85.7±13.2）%、（51.9±17.6）%。结论孤立性髓系肉瘤较白血病性髓系肉瘤生存有更好的趋势。髓系肉瘤的生存与髓系疾病的类型及不良预后因素也有关。
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| 关 键 词： | 髓系肉瘤 临床特征 生存分析 |
| 收稿时间： | 2013-01-04 |
Clinical Manifestation and Survival Analysis with Myeloid Sarcoma |
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| GAO Rupan,ZOU Shanhua,LI Feng,WANG Weiguang,CHENG Zhixiang,YUAN Ling,CHENG Yunfeng.Clinical Manifestation and Survival Analysis with Myeloid Sarcoma[J].Cancer Research on Prevention and Treatment,2013,40(6):538-540. |
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| Authors: | GAO Rupan ZOU Shanhua LI Feng WANG Weiguang CHENG Zhixiang YUAN Ling CHENG Yunfeng |
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| Institution: | Department of Hematology,Zhongshan Hospital,Fudan University,Shanghai 200032,China |
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| Abstract: | ObjectiveTo investigate the clinical manifestations,treatment and prognosis of myeloid sarcoma(MS).MethodsClinical data of 17 MS cases were retrospectively analyzed.Survival analysis was made by Kaplan-Meier method.ResultsThe predilection sites had lymph nodes,breast,cervix and orbit.Eight cases of isolated myeloid sarcoma and 9 case leukemia myeloid sarcoma were observed.The overall survival rate at 1 year was （72.0±12.0）% and 3 years （45.7±14.4）%.The overall survival rate of 3 year in isolated myeloid sarcoma was （85.7±13.2）%，and （51.9±17.6）% in leukemia.ConclusionPrognosis in isolated myeloid sarcoma was better than that in leukemia myeloid sarcoma.Survival of myeloid sarcoma was related to types of disease and adverse prognostic factors. |
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| Keywords: | Myeloid sarcoma(MS) Clinical manifestation Survival analysis |
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