Tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces cell proliferation in normal human bronchial epithelial cells through NFkappaB activation and cyclin D1 up-regulation |
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| Authors: | Ho Yuan-Soon Chen Chien-Ho Wang Ying-Jan Pestell Richard G Albanese Chris Chen Rong-Jane Chang Mei-Chi Jeng Jiiang-Huei Lin Shyr-Yi Liang Yu-Chih Tseng How Lee Wen-Sen Lin Jen-Kun Chu Jan-Show Chen Li-Ching Lee Chia-Hwa Tso Wei-Ling Lai Yann-Chwen Wu Chih-Hsiung |
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| Affiliation: | Graduate Institute of Biomedical Technology, Taipei Medical University, Taipei, Taiwan. |
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| Abstract: | |
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| Keywords: | NNK, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone NHBE, normal human bronchial epithelial cell SAEC, small airway epithelial cell nAchR, nicotinic acetylcholine receptor DHβE, dihydro-β-erythroidine α-BTX, α-bungarotoxin MLA, methyllycaconitine MCA, mecamylamine α-ATX, α-anatoxin |
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