| 复方银屑颗粒治疗小鼠银屑病模型的实验研究 |
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| 引用本文： | 谭梦晖,金若敏,庞惠芳,周志兰,韩正宾,许伟国. 复方银屑颗粒治疗小鼠银屑病模型的实验研究[J]. 上海中医药大学学报, 2008, 22(2): 48-49 |
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| 作者姓名： | 谭梦晖 金若敏 庞惠芳 周志兰 韩正宾 许伟国 |
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| 作者单位： | 上海中医药大学中药学院,上海,201203;安徽宿洲绿源中医药科技有限公司,安徽,宿县234000 |
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| 基金项目： | 国家"863"计划基金资助项目(2003AA223518) |
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| 摘 要： | 目的：探讨复方银屑颗粒对小鼠银屑病模型的治疗作用。方法：小鼠灌服给予复方银屑颗粒后，观察药物对小鼠阴道上皮细胞有丝分裂以及鼠尾鳞片表皮颗粒细胞数的变化。结果：复方银屑颗粒能明显降低小鼠阴道上皮细胞有丝分裂、促进鼠尾表皮颗粒细胞形成。结论：复方银屑颗粒对小鼠银屑病模型有较好的治疗作用。
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| 关 键 词： | 银屑病 复方银屑颗粒 动物模型 |
| 文章编号： | 1008-861X(2008)02-0048-02 |
| 修稿时间： | 2007-12-25 |
Experimental Research on "Compound Yinxie Granule" in Treating Mice Psoriasis |
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| TAN Meng-hui,JIN Ruo-min,PANG Hui-fang,ZHOU Zhi-lan,HAN Zheng-bin,XV Wei-guo. Experimental Research on "Compound Yinxie Granule" in Treating Mice Psoriasis[J]. Acta Universitatis Traditionis Medicalis Sinensis Pharmacologiaeque Shanghai, 2008, 22(2): 48-49 |
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| Authors: | TAN Meng-hui JIN Ruo-min PANG Hui-fang ZHOU Zhi-lan HAN Zheng-bin XV Wei-guo |
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| Affiliation: | TAN Meng-hui, JIN Ruo-min, PANG Hui-fang, ZH0U Zhi-lan, HAN Zheng-bin, XV Wei-guo( 1. Shanghai University of Traditional Chinese Medicine ; 2. Suzhou Luyuan Technology. Limited Company of TCM, Anhui) |
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| Abstract: | Objective： To investigate the effects of ＂Compound Yinxie Granule＂ on mice psoriasis. Methods： After oral administration of ＂Compound Yinxie Granule＂, its therapeutical effects against psoriasis were observed with animal models of vaginal epithelium cell mitosis and scaled tail epidermis in mice. Results： ＂Compound Yinxie Granule＂ could inhibit the mitosis of mouse vaginal epithelia, and promote the formation of cuticular granular cells on scaled epidermis of mouse tail significantly. Conclusion： ＂Compound Yinxie Granule＂ exhibits a beneficial influence on mice psoriasis. |
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| Keywords: | Psoriasis ＂Compound Yinxie Granule＂ animal model |
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