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Comparison of Intestinal Permeabilities Determined in Multiple in Vitro and in Situ Models: Relationship to Absorption in Humans |
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| Authors: | Stewart Barbra H. Chan O. Helen Lu Rosalind H. Reyner Eric L. Schmid Heidi L. Hamilton Harriet W. Steinbaugh Bruce A. Taylor Michael D. |
| Affiliation: | (1) Department of Pharmacokinetics/Drug Metabolism, Parke-Davis Pharmaceutical Research, Division of Warner-Lambert Company, 2800 Plymouth Road, Ann Arbor, Michigan, 48105;(2) Department of Chemistry, Parke-Davis Pharmaceutical Research, Division of Warner-Lambert Company, 2800 Plymouth Road, Ann Arbor, Michigan, 48105 |
| Abstract: | |
| Keywords: | absorption of peptidomimetics CACO-2 cell model intestinal absorption models fraction absorbed in humans rat everted intestinal ring model rat intestinal perfusion model |
| 本文献已被 SpringerLink 等数据库收录！ | |