| 装饰材料挥发物遗传毒性研究 |
| |
| 引用本文： | 余淑苑, 张志诚, 康莉, 王秀英, 庄志雄, 黄钰, 赵婷. 装饰材料挥发物遗传毒性研究[J]. 中国公共卫生, 2002, 18(10): 1205-1206. DOI: 10.11847/zgggws2002-18-10-33 |
| |
| 作者姓名： | 余淑苑 张志诚 康莉 王秀英 庄志雄 黄钰 赵婷 |
| |
| 作者单位： | 1.深圳市疾病预防控制中心 518020;;2.中山大学 |
| |
| 基金项目： | 深圳市科委项课题:1999(04040) |
| |
| 摘 要： | 目的研究装饰材料挥发物对人体外周血淋巴细胞DNA损伤作用。方法应用单细胞凝胶电泳法分别检测在装修场所与未装修场所工作半年女服务员外周血淋巴细胞DNA损伤。结果在新装修场所工作半年服务员其外周血淋巴细胞DNA断裂比对照组要高,其差别有显着性意义(P<0.01)。结论装饰材料挥发物可引起人们外周血淋巴细胞DNA损伤,从而提示SCG检测DNA损伤可作为有害因素对健康影响的早期生物学标记。
|
| 关 键 词： | 单细胞凝胶电泳 装饰材料 遗传毒性 |
| 文章编号： | 1001-0580(2002)10-1205-02 |
| 收稿时间： | 2002-01-21 |
| 修稿时间： | 2002-01-21 |
Study on Genetic Toxicity of Volatile Compounds of Decorated Materials |
| |
| YU Shu-yuan, ZHANG Zhi-cheng, KANG Li, . Study on Genetic Toxicity of Volatile Compounds of Decorated Materials[J]. Chinese Journal of Public Health, 2002, 18(10): 1205-1206. DOI: 10.11847/zgggws2002-18-10-33 |
| |
| Authors: | YU Shu-yuan ZHANG Zhi-cheng KANG Li |
| |
| Affiliation: | 1.Shenzhen Centre for Disease Prevention and Control, Shenzhen 518020, China |
| |
| Abstract: | ObjectiveTo study on DNA damage of human peripheral lymphocytes caused by the volatile compounds of decorated materials.MethodsThe alkaline single cell gel electrophoresis(SCGE)was used to detect the DNA damage of peripheral lymphocytes of woman servants worked in decorated areas or not for half year.ResultsThe rate of DNA damage of the women working in the decorated room was higher than that of the control group.(P<0.01).ConclusionThe volatile componds of decorated materials may do harm on the DNA of human peripheral lymphocytes,and the DNA damage can be detected by SCGE method as an early biological indicator. |
| |
| Keywords: | SCGE decorated material genetic toxicity |
| 本文献已被 维普 万方数据 等数据库收录！ |
| 点击此处可从《中国公共卫生》浏览原始摘要信息 |
|
点击此处可从《中国公共卫生》下载全文 |
