HIV/AIDS患者抗逆转录病毒治疗退出影响因素研究进展

艾滋病是由人类免疫缺陷病毒(H1V)引起的一种危害性极大的传染病,需要HIV/AIDS患者每日按时按量服药才能有效抑制体内HIV复制.中国实施抗逆转录病毒疗法(ART)和扩大治疗策略将所有符合条件的HIV感染者纳人治疗范围,越来越多的HIV感染者接受ART,同时退出(停药和失访)ART的HIV/AIDS患者人数也在逐年...

Research progress on influencing factors of antiretroviral therapy withdrawal in HIV/AIDS patients

AIDS is a highly harmful infectious disease caused by human immunodeficiency virus(HIV), which requires HIV/AIDS patients to take medication on time and at the appropriate amount every day to effectively inhibit HIV replication in vivo. China has implemented antiretroviral therapy(ART) and expanded treatment strategy, including all eligible HIV-infected people into the treatment scope of treatment. More and more HIV-infected patients receive ART. At the same time, the number of HIV/AIDS patients who withdraw from ART(drug withdrawal and loss of follow-up) is also increasing year by year. In the long-term medication process of HIV/AIDS patients, various reasons such as adverse drug reactions, busy work, CD4, low selfmanagement ability of patients, economic conditions and other reasons lead to poor compliance of patients and high incidence of withdrawal. In China, ART treatment coverage of HIV/AIDS patients is required to be over 90%, and withdrawal has become the biggest threat to the coverage of ART treatment. In this paper, the influencing factors related to ART withdrawal of HIV/AIDS patients were summarized to comprehensively understand the reasons for the possible withdrawal of ART therapy for HIV/AIDS patients, and to provide measures to reduce the withdrawal and loss of follow-up of ART therapy for HIV/AIDS patients.