丹参饮加减治疗心血瘀阻型微血管性心绞痛的临床观察

【目的】观察丹参饮加减治疗心血瘀阻型微血管性心绞痛的临床疗效。【方法】将60例心血瘀阻型微血管性心绞痛患者随机分为对照组和治疗组,每组各30例。对照组给予西医常规治疗,治疗组在此基础上配合丹参饮加减治疗,疗程为4周。观察2组患者治疗前后中医证候积分的变化情况,评价2组患者的心绞痛疗效和心电图疗效。【结果】(1)心绞痛疗效方面:治疗4周后,治疗组的总有效率为93.3%(28/30),对照组为83.3%(25/30),治疗组的心绞痛疗效优于对照组,差异有统计学意义(P<0.05)。(2)中医证候积分方面:治疗4周后,2组患者的中医证候积分均较治疗前明显降低(P<0.05),且治疗组的降低作用明显优于对照组,差异有统计学意义(P<0.05)。(3)心电图疗效方面:治疗4周后,治疗组的总有效率为90.0%(27/30),对照组为76.7%(23/30),治疗组的心电图疗效优于对照组,差异有统计学意义(P<0.05)。【结论】在西医常规治疗基础上配合丹参饮加减治疗心血瘀阻型微血管性心绞痛患者疗效确切,其疗效优于单纯西医常规治疗。

Clinical Observation on Modified Danshen Decoction for the Treatment of Microvascular Angina Pectoris with Syndrome of Heart Blood Stagnation

Objective To observe the clinical effect of modified Danshen Decoction for the treatment of microvascular angina pectoris of heart blood stagnation type.Methods Sixty patients with microvascular angina pectoris of heart blood stagnation type were divided into control group and treatment group,with 30 patients in each group.The control group was treated with conventional western medicine treatment,and the treatment group was given modified Danshen Decoction combined with conventional western medicine treatment.The course of treatment lasted for 4 weeks.The changes in the traditional Chinese medicine(TCM)syndrome scores before and after treatment in the two groups were observed.And after treatment,the efficacy for angina pectoris and the efficacy for electrocardiogram in the two groups were evaluated.Results(1)After treatment for 4 weeks,the total effective rate for angina pectoris in the treatment group was 93.3%(28/30),and that in the control group was 83.3%(25/30).The intergroup comparison showed that the efficacy for angina pectoris in the treatment group was superior to that in the control group,and the difference was statistically significant(P<0.05).(2)After treatment for 4 weeks,the TCM syndrome scores in the two group were obviously decreased in comparison with those before treatment(P<0.05),and the decrease in the treatment group was superior to that in the control group,the difference being statistically significant(P<0.05).(3)After treatment for 4 weeks,the total effective rate for electrocardiogram in the treatment group was 90.0%(27/30),and that in the control group was 76.7%(23/30).The intergroup comparison showed that the efficacy for electrocardiogram in the treatment group was superior to that in the control group,and the difference was statistically significant(P<0.05).Conclusion Modified Danshen Decoction combined with conventional western medicine treatment has definite curative effect on patients with microvascular angina pectoris of heart blood stagnation type,and its effect is stronger than that of the conventional western medicine treatment alone.