| 复元散对激素性股骨头坏死生化代谢影响的实验研究 |
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| 引用本文： | 许书亮,洪加源.复元散对激素性股骨头坏死生化代谢影响的实验研究[J].中国中医骨伤科杂志,1998,6(6):8-12. |
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| 作者姓名： | 许书亮 洪加源 |
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| 作者单位： | 福建中医学院骨伤系 |
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| 基金项目： | 福建省科委自然科学基金 |
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| 摘 要： | 通过观察复元散对激素性股骨头坏死生化代谢的影响。探讨复元散对激素性股骨头坏死的作用机理。４０只雄性新西兰白兔，随机分成模型组激素＋复元散组和空白对照组，每隔２周分别进行生化测定。结果显示：Ａ组血清钙，钙磷乘积及骨钙均明显低于Ｂ，Ｃ组，氨基已糖，羟脯氨酸含量及骨钙盐，氨基已糖与羟脯氨酸比值亦呈下降趋势，低于Ｂ，Ｃ组。表明复元散可促进生化代谢，纠正负钙平衡，促进基质合成和钙磷沉积。
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| 关 键 词： | 中医药疗法 激素性 股骨头坏死 生化代谢 复原散 |
Experimental Study of Fu Yuan San on Biochemistry Metablism of Steroid-induced Necrosis of Femoral Head in Rabbits |
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| Xu Shuliang,Hong Jiayuan Fujian College of Traditional Chinese Medicine,Fu Zhou.Experimental Study of Fu Yuan San on Biochemistry Metablism of Steroid-induced Necrosis of Femoral Head in Rabbits[J].Chinese Journal of Traditional Medical Traumatology & Orthopeics,1998,6(6):8-12. |
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| Authors: | Xu Shuliang Hong Jiayuan Fujian College of Traditional Chinese Medicine Fu Zhou |
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| Institution: | Xu Shuliang,Hong Jiayuan Fujian College of Traditional Chinese Medicine,Fu Zhou 350003 |
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| Abstract: | The experiment study the effects of Fu Yuansan (FYS) on biochemistry metabolism of steroid-induced necrosis of femoral head (SINFH).Forty male New Zealand rabbits were radomly divided into model group (A),steroid and FYS group (B) and control group (C).The biochemistry indicators were measured every two weeks.The results showed the serum-calcium,serun-calcium-phosphorous-product and osteocalcium of group A were obiously lowest than those the group B and C (P<0.01,P<0.001);Hexosamine (HOM),hydroxyproline (HOP) and the ratios of Ca/HOP and HOM/HOP of group A were also lowest than those of group B and C (P<0.05) .It indicated that the FYS can improve biochemistry metabbolism,namely can correct negative calcium balance,improve syntheses of martix and increase of calcium and phosphorous. |
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| Keywords: | TCM-therapy Steroid-induced necrosis of femoral head Biochemistry metabolism Experimental study |
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