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Mupirocin resistance in Staphylococcus aureus in an Indian hospital
Authors:Gadepalli Ravisekhar  Dhawan Benu  Mohanty Srujana  Kapil Arti  Das Bimal K  Chaudhry Rama  Samantaray J C
Affiliation:Department of Microbiology, All India Institute of Medical Sciences, New Delhi-29, India.
Abstract:Two hundred Staphylococcus aureus strains collected from an Indian hospital were tested for mupirocin susceptibility using disc diffusion method and E-test. High-level and low-level mupirocin resistance was detected in 10 (5%) and 2 (1%) S. aureus strains, respectively. Pulsed-field gel electrophoresis analysis of the high-level mupirocin-resistant methicillin-resistant S. aureus isolates revealed the presence of 2 clones with the majority of strains belonging to 1 clone, suggesting clonal dissemination.
Keywords:Antimicrobial susceptibility   Staphylococcus aureus   Multiplex PCR   Mupirocin resistance   Methicillin resistance
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