Clinical observation on the efficacy of Xiaoshui decoction (消水方) combined with intrapleural perfusion of cisplatin in treating malignant pleural effusion |
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引用本文: | 施展,何庆勇,花宝金.Clinical observation on the efficacy of Xiaoshui decoction (消水方) combined with intrapleural perfusion of cisplatin in treating malignant pleural effusion[J].Chinese Journal of Integrated Traditional and Western Medicine,2008,14(4):257-261. |
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作者姓名: | 施展 何庆勇 花宝金 |
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作者单位: | Guang'anmen Hospital,China Academy of Chinese Medical Sciences |
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摘 要: | Objective: To observe the clinical efficacy of Xiaoshui decoction (XSD,消水方) combined with intrapleural perfusion of cisplatin in the treatment of malignant pleural effusion. Methods: Fifty-one patients with malignant pleural effusion were randomly assigned to two groups. The treated group patients) received oral administration of XSD combined with intrapleural perfusion of cisplatin, and control group (25 patients) was only treated with intrapleural perfusion of cisplatin. The effects of 26 he he short-term efficacy, quality of life scores and clinical symptom scores of malignant pleural effusion were evaluated. Results: The short-term efficacy in the treated group and the control group was 72.0% and 58.3%, respectively, and no significant difference was found (P〉0.05). In contrast, the quality of life in the treated group was significantly improved compared to that of the control group (P〈0.05), and so was the symptom remission (P〈0.05). Conclusions: The combined therapy of XSD and intrapleural perfusion of cisplatin did not show obvious improvement in short-term efficacy, but the therapy remarkably alleviated the symptoms and improved the quality of life of patients.
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关 键 词: | 消水方 恶性胸膜渗出 临床效果 治疗方法 |
Clinical observation on the efficacy of Xiaoshui decoction (消水方) combined with intrapleural perfusion of cisplatin in treating malignant pleural effusion |
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Authors: | Zhan Shi Qing-yong He and Bao-jin Hua |
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Abstract: | Objective To observe the clinical efficacy of Xiaoshui decoction (XSD, 消水方) combined with intrapleural perfusion of cisplatin in the
treatment of malignant pleural effusion.
Methods Fifty-one patients with malignant pleural effusion were randomly assigned to two groups. The treated group (26 patients) received
oral administration of XSD combined with intrapleural perfusion of cisplatin, and the control group (25 patients) was only
treated with intrapleural perfusion of cisplatin. The effects of the short-term efficacy, quality of life scores and clinical
symptom scores of malignant pleural effusion were evaluated.
Results The short-term efficacy in the treated group and the control group was 72.0% and 58.3%, respectively, and no significant difference
was found (P>0.05). In contrast, the quality of life in the treated group was significantly improved compared to that of the control group
(P<0.05), and so was the symptom remission (P<0.05).
Conclusions The combined therapy of XSD and intrapleural perfusion of cisplatin did not show obvious improvement in short-term efficacy,
but the therapy remarkably alleviated the symptoms and improved the quality of life of patients. |
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Keywords: | Xiaoshui decoction malignant pleural effusion cisplatin clinical efficacy |
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