毒鼠强中毒15例临床分析

观察了 15例经血中毒物定性分析确定为毒鼠强中毒的急诊病人的临床症状 ,并分析了各种急诊处理的疗效。结果发现 :15例毒鼠强中毒患者均不能仅通过病史和临床症状与氟乙酰胺等毒物中毒区分 ,必须进行毒物分析来获得可靠的诊断。在毒鼠强中毒的病例中早期洗胃的效果较好 ,13例出现惊厥的病例进行血浆置换治疗后惊厥症状立即缓解 ,4例应用机械通气的病例镇静剂用量比其它病例大 ,惊厥症状控制得比其它病例更满意。提示早期洗胃和尽早进行毒物分析至关重要 ;对于使用血浆置换治疗和气管切开术、机械通气治疗应持更积极的态度。

Clinical analysis of 15 cases with tetramethylenedisulfotetramine

In our study, we observed the clinical manifestations of 15 tetramethylenedisulfotetramine (TEM) toxicosis emergency patients diagnosed by plasma toxin chemical analysis, and evaluated the effect of emergency treatments. All cases could not be differentiated from the other kinds of toxicosis by clinical manifestations,and toxin chemical analysis was the sole definite diagnosis method. The effect of gastric lavage in early stage was especially obvious, 13 cases with convulsions got immediate relief after plasma exchange, the use of large dosage of tranquilizer resulted in better control on convulsion in 4 cases treated with ventilator than that in the others. Gastric lavage and chemical toxin analysis in early stage are of vital importance, plasma exchange, tracheotomy and machanical ventilation are the most effective treatment methods. [