慢性心力衰竭患者贫血异常检测的相关因素研究

目的：研究慢性心力衰竭（CHF）患者贫血异常检测的相关因素。方法选择沭阳县中心医院心内科2007年12月至2012年12月住院患者150例，均经3名以上有经验的临床执业医师诊断后确诊为CHF，诊断标准为中华医学会心血管病分会推荐的CHF诊断标准，排除由血液系统疾病导致的贫血者。另选择沭阳县中心医院体检中心健康体检者150例作为对照组，男75例，女75例，年龄（55±14）岁。比较各组患者一般资料、肾功能、全血细胞分析参数、左室射血分数（LVEF）和生化参数。结果贫血组患者年龄与非贫血组相比显著升高，差异有统计学意义（P＜0．01）；男性明显高于女性，差异有统计学意义（P＜0．05）；是否贫血、贫血的程度与肾功能障碍呈正相关（P＜0．05）；CHF组与对照组相比，其血红蛋白、红细胞比容、LVEF明显降低，差异有统计学意义（P＜0．01），生化分析血肌酐明显升高，差异有统计学意义（P＜0．01）。结论CHF患者大多伴有贫血，其相关程度均为正相关，而年龄、性别和心、肾功能均为CHF患者贫血异常检测的相关因素。

A study on relevant factors of chronic cardiac failure combined with abnormal anemia

Objective To study the relevant factors of chronic cardiac failure with abnormal anemia . Methods Onehundred and fifty patients were collected from December 2007 to December 2012 .All of them were di-agnosed as CHF by more than 3 experienced medical practitioners according to the CHF diagnostic creteria recom-mended by the Cardiovascular disease branch of Chinese Medical Association .Patients sufferred from hematological system diseases were excluded .In addition ,150 healthy people of the physical examination center in our hospital were chosen as the control group including 75 males and 75 females ,and their average age was （55 ± 14） .The general in-formation ,renal function ,whole blood cell analysis ,LVEF and biochemical parameter were compared between the two groups .Results The datas in anemia group were significant higher than that in non-anemia group（P〈0 .01） ,and da-tas of male were significant higher than the female（P〈0 .05）;whether they were anemia or not ,the degree of anemia were positively correlated with renal dysfunction （P〈 0 .05）;Hb ,HCT ,LVEF of the CHF group were significant lower than that of the control group（P〈0 .01） ,but SCr is significant higher（P〈0 .01） .Conclusion Patients with CHF often accompanies with anemia ,and their relationship is positive .In addition ,age ,gender ,cardiac function and renal function are all the related factors for the abnormal anemia of CHF .