非小细胞肺癌患者手术与非手术治疗的疗效及预后分析 |
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引用本文: | 陈勇吉,李志强,江向明.非小细胞肺癌患者手术与非手术治疗的疗效及预后分析[J].检验医学与临床,2013(23):3140-3141. |
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作者姓名: | 陈勇吉 李志强 江向明 |
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作者单位: | 四川省崇州市人民医院胸外科,611230 |
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摘 要: | 目的比较非小细胞肺癌(NSCLC)手术与非手术治疗的临床疗效和预后。方法将116侧N骶LC患者根据是否予以手术治疗分为手术组和非手术组,每组各58例。手术组予以手术根除性切除联合放疗和化疗治疗;非手术组则只运用放疗和化疗治疗。结果手术组总体有效率为79.31%,显著优于非手术组的24.13%,差异有统计学意义(P〈0.05);且毒副作用的发生率均低于非手术组,差异有统计学意义(P〈0.05);手术组的局部复芡率、远处转移率、局部复发并远处转移率均明显低于非手术组,且1、3、5年的生存率明显升高,差异均有统计学意义(P〈0.05)。结论以手术为主的多学科综合治疗方式可提高NSCLC患者生存率,降低毒副作用、局部复发和肿瘤转移。
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关 键 词: | 非小细胞肺癌 放疗 化疗 手术治疗 |
Analysis on the clinical efficacy and prognosis between surgery and non-surgical treatment in non-small cell lung cancer |
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Institution: | CHEN Yong ji ,L I Zhi-qiang , J IANG Xiang-ming (Department of Chest Surgery, People's Hospital of Chong-zhou City, Chongzhou, Sichuan 611230, China) |
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Abstract: | Objective To compare clinical efficacy and prognosis between surgical and non-surgical treatment in patients with non-small cell lung cancer(NSCLC). Methods A total of 116 cases with NSCLC were randomly di- vided into surgical treatment group and non surgical treatment group, fifty eight cases in each group. Surgical therapy group received surgery, chemotherapy and radio'~herapy ~while "*he non-surgical group only received chemotherapy, llt~ suits Overall effective in combined therapy group was 79.31 ~/00, which significantly higher than non surgical treat- ment group with 24.13 ~J00 (P~0.05), and the rate of toxic and side effects were lower than the non surgical treatment group(P〈~0.05). Local recurrence, distant metastasis rate, and the local recurrence combined with distant metastasis were significantly lower than the surgery group,and the 1,3,5-year survival rates were significantly higher than the non-surgical group(P〈0.05). Conclusion Surgical treatment of NSCLC patients can improve survival rates,reduce toxicity,local recurrence and tumor metastasis. |
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Keywords: | non--small cell lung cancer radiotherapy chemotherapy~ surgery |
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