| 泌尿生殖道支原体感染及体外药敏试验分析 |
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| 引用本文： | 陈蓓,吴天鹏,欧阳海. 泌尿生殖道支原体感染及体外药敏试验分析[J]. 临床泌尿外科杂志, 2008, 23(10) |
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| 作者姓名： | 陈蓓 吴天鹏 欧阳海 |
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| 作者单位： | 1. 武汉大学人民医院皮肤性病科,武汉,430060
2. 武汉大学人民医院泌尿外科,武汉,430060 |
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| 摘 要： | 目的:分析本地区解脲脲原体(Uu)和人型支原体(Mh)的感染状况和耐药性,并对耐药机制进行讨论.指导临床合理用药.方法:对1 612例疑为非淋菌性尿道炎(NGU)患者的泌尿生殖道标本进行支原体检测,并对阳性标本进行抗生素敏感试验.结果:1612例标本中,支原体检出1160例,感染率为72%.其中Uu、Mh、Uu Mh感染率分别为71%、19.7%、9.3%,Uu感染明显高于Mh感染,男性Uu感染率(75.5%)高于女性(68%),女性Mh感染率(22.1%)高于男性(16.0%),总感染率女性(59.6%)高于男性(40.4%),差异有统计学意义(P＜0.05).Uu和Mh对强力霉素、交沙霉素、原始霉素较为敏感.耐药率都在5%以下.Uu和Mh对氟喹诺酮类药物耐药率较高.Mh对红霉素、阿奇霉素、克拉霉素耐药率较高.而Uu对其敏感.结论:NGU患者中支原体是主要病原体之一,鉴于耐药菌株的不断变化,建议在进行支原体检测时进行药敏试验,加强对耐药性的监测,并对其耐药机制进行深入研究,对指导临床治疗具有重要意义.新一代四环素类药物可作为Uu和Mh感染的一线药物.
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| 关 键 词： | 泌尿生殖道感染 药敏试验 |
Study Mycoplasma infection in genitourinary tract and the antimicrobial susceptibility test in vitro |
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| CHEN Bei,WU Tianpeng,OU Yanghai. Study Mycoplasma infection in genitourinary tract and the antimicrobial susceptibility test in vitro[J]. Journal of Clinical Urology, 2008, 23(10) |
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| Authors: | CHEN Bei WU Tianpeng OU Yanghai |
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| Affiliation: | 1Department of Derm-Venerology;the Third Hospital of Wuhan;Wuhan;430060;China;2Department of Urology;Renmin Hospital of Wuhan University |
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| Abstract: | Objective:To evaluate the infection and resistance of ureaplasma urealyticum (Uu) and mycoplasma hominis (Mh), probe into the mechanism of resistance, in order to determine the most suitable treatment.Methods:Mycoplasma in genitourinary tract of 1 612 patients who were suspected non-gonococcal urethritis (NGU) was detected, and proceeded the antimicrobial susceptibility test (AST) in positive samples. Results:In 1 612 tested samples, 1 160 cases were Mycoplasma positive (72%). The infective rates of Uu, Mh,... |
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| Keywords: | Mycoplasma infection Antimicrobial susceptibility test |
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