新疆维吾尔族、汉族妇女宫颈液基细胞学检查结果分析

目的通过薄层液基细胞学（LCT）检查方法，比较新疆地区维吾尔族（维族）、汉族妇女宫颈病变发病情况。方法对新疆自治区人民医院妇产科就诊的11841例汉族、维族及其他少数民族妇女进行宫颈液基细胞学检查，对阳性（≥ASCUS）结果进行阴道镜及病理检查，并对各年龄组进行比较分析。结果经液基细胞学检查，在结果≥ASCUS的患者中，汉族为1402（23．63％）例，其中ASCUS：1341（22．60％）例、ASC—H：10（0．17％）例、LSIL：34（O．57％）例、HSIL：10（0．17％）例、SCC／AC：7（0．12％）例。维族：1470（27．89％）例，分别为1375（26．09％）例、11（0．21％）例、48（0．91％）例、22（0．42％）例、14（O．27％）例。阴道镜下取活组织检查，病理学符合率分别为ASCUS：76．32％、ASC—H：66．67％、LSIL（cINI）：84．88％、HSIL（CINⅡ-Ⅲ）：87．88％、SCC／AC：100％。在年龄组分布中，汉族和维族在241岁组中宫颈病变的发病率随着年龄的增长而增加，维族在〈40岁组中阳性检出率较汉族妇女高，60岁前维族和汉族阳性检出率的差异有统计学意义（P〈O．01），在结果CINI组的比较中，汉族和维族阳性检出率的差异有统计学意义（P〈0．01）。结论新疆宫颈癌发病率在维族和汉族妇女中存在明显的民族差异，开展液基细胞学检查，对检出宫颈病变具有重要意义。

Results of cervical LCT in Uygur and Han women in Xinjiang Uygur Autorlomous Region

Objection To survey the cervical lesions in Uygur women and Hart women in Xinjinag area through the technology of liquid-based cytologic test （LCT）. Methods Cervical lesion of 11 841 Uygur women and Han women and the other minorities in department of obstetrics and gynecology of Xinjiang Region People＇s Hospital were examined by cervical LCT. Those having a positive result （〉~ASCUS） were examined with eolposcopy and pathology,the results in each age group were compared and analyzed. Results LCT results showed that among the women with ~〉ASCUS there were l 402（23.63%） Han women and ASCUS,ASC-H, LSIL, HSIL and SCC/AC were detected in 1341 （22.60%）, 10（0.17%）,34 （0.57%）, 10（0.17%）,7（0.12%） 1470 of them. While among the Uygur women with ~〉ASCUS,the ASCUS,ASC-H,LSIL, HSIL and SCC/AC were detected in 1375（26.09%）, 11 （0.21%）,48（0.91%）,22（0.42%） and 14（0.27% ） of them. The coincidence rates of LCT and biopsy for ASCUS, ASC-H, LSIL （CIN I ）, HSIL （CIN I]- III ） and SCC/AC were respectively 76.32% ,66.67% ,84.88% , 87.88% and 100%o The incidence rates of cervical lesions in Han and Uygur women older than 40 years old were increased along with the increase of age. The incidence rate of cervical lesions in Uygnr women younger than 40 years old was higher than that of Han women and significant difference was observed in Uygnr women older than 60 years old （P〈0.01） eomp;ared to Han women in the same age group. Conclusions The incidence of cervical cancer is significantly different in Uygur and Han women in Xinjiang and LCT is of great importance in detect ion of incidence of cervical lesions.