海南省2010年麻疹强化免疫效果评价

摘要：目的分析评价海南省2010年麻疹减毒活疫苗（Mv）强化免疫效果。方法综合分析麻疹强化免疫接种率、麻疹监测系统资料及AEFI监测系统资料。结果全省强化免疫共接种8月龄～6岁目标儿童772850人，报告接种率为96．93％，其中常住儿童报告接种率为97．05％，流动儿童报告接种率96．19％，两组人群强化免疫接种率差异有统计学意义（x2=-253．557，P〈0．05），分年龄组报告接种率均〉95％，系统评估接种率为97．7％，调查两市县接种率无统计学意义（x2=0．812，P〉0．05），2010年、2011年、2012年全省麻疹发病率分别为0．5／100万，0．47／100万、0．33／100万。结论海南省2010年开展NV强化免疫进一步提高了8月龄～6岁儿童MV的接种率，确保了适龄儿童MV抗体水平，并形成人群有效的免疫屏障，从而巩固了我省提前消除麻疹的现有成绩，但是要确保实现2012年消除麻疹的目标，必须在确保常规免疫高接种率的同时进一步提高mv及时接种率，同时开展流动人口查漏补种工作。

Evaluation on supplementary immunization activities of measles attenuated live vaccine in Hainan in 2010

Abstract：Objective To evaluate the effect of supplementary immunization activity（SIA）of measles vaccine in Hainan province. Methods The data of inoculation rate of SIA,and the data from measles surveillance system and AEFI surveillance system were collected and synthetically analyzed. Results 772850 targeted children 6 months to 8 years old were vaccinated in the SIA of measles vaccine, and the reported inoculation rate was 96.93%, of which the local children was 97.05%, and the migrant children was 96.19%, there was statistical difference between two groups（x2=253.557, P〈0.05）. The reported inoculation rate of each age group of MV SIA was〉95%,and the evaluated inoculation rate was 97.7% ,there was no statistical difference between inoculation rates of two cities surveyed （X2=0.812 ,P〉0.05）.The Incidence rates of measles from 2010 to 2012 were 0.5/1 000 000,0.47/1 00 000,0.33/1 000 000 respectively. Conclusions The SIA of MV of Hainan province in 2010 increased the inoculation rate of children aged from 6 months to 8 years,and ensured the MV antibody levels of aged ehLldren,and formed effective immune barrier in crowd,in general,the MV SIA consolidated the present achievement of elimination of measles in advance in Hainan. For realizing the goal of Measles elimination in 2012,it is necessary to improve and maintain high inoculation rate and timely coverage rate of routine immunization, and carry out timely vaccination for the floating population simultaneously.