A highly sensitive enzyme-linked immunosorbent assay to quantitate antibodies to Epstein-Barr virus membrane antigen gp340 |
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| Authors: | B J Randle M A Epstein |
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| Affiliation: | Department of Pathology, University of Bristol, The Medical School, University Walk, Bristol, BS8 1TD, U.K. |
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| Abstract: | An enzyme-linked immunosorbent assay (ELISA) has been developed for the detection of antibodies to Epstein-Barr (EB) virus membrane antigen (MA) glycoprotein, gp340, in tamarins. The assay was found to be a thousand-fold more sensitive than conventional indirect immunofluorescence tests and consequently it was possible to follow accurately the sequential production of specific antibodies to gp340 by tamarins during a course of immunization. |
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| Keywords: | ELISA Epstein-Barr virus membrane antigen antibodies to EBV, MA gp340 Epstein-Barr virus Epstein-Barr virus vaccine |
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