新生儿缺氧缺血性脑病早期干预的研究

目的：探讨早期综合干预对新生儿缺氧缺血性脑病（HIE）预后的影响。方法：将66例轻、中、重度缺氧缺血性脑病患儿随机分为干预组（34例）和对照组（32例）,两组基本情况差异无显著性。对干预组进行系统的早期干预、医学干预、营养干预以及康复训练,而对照组常规育儿及保健指导。于生后3、6、9、12、18、24、36个月均进行发育商及智能发育检测。结果：干预组平均发育商明显高于对照组（P〈0.01）。结论：早期干预能改善HIE的预后,降低脑瘫及智能发育落后。

Study on Early Intervention of the Neonates with Hypoxic Ischemic Encephalopathy

Objective:To study the effect of early intervention on neonates with hypoxic-ischemic encephalopathy(HIE).Methods: 66 cases of neonates with slight,medium and severe HIE were studied and divided stochastically into two groups :early intervention was done for 34 cases,called Group A,with 32 cases untreated as Group B.There was no difference in general condition between group A and group B.Early systemic,medical and nutritious intervention as well as recovery training was done on group A while untreated group B was done and directed according to the regularity.Results: Average scores of mental development quotient in group A were higher than in group B at the ages of 3rd,6th 9th,12th,24th and 36th month(P<0.01).Conclusions: The prognosis of HIE will be improved with early intervention.The morbidity of cerebral palsy and mental retardation can be decreased as well .