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The role of econazole in the management of oculomycosis |
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| Authors: | E. O. Oji Y. M. Clayton |
| Affiliation: | (1) Ophthalmology Unit Department of surgery, University of Jos, Plateau State, Nigeria;(2) Institute of Dermatology St. John's Hospital for deseases of the skin, Lisle Street, WC2, London, UK |
| Abstract: | The possible role of econazole in the management of fungal eye infections is presented in this study. An animal model of oculomycosis was used to demonstrate the efficacy of econazole in an in vivo system both as a prophylactic and as a powerful therapeutic agent against sensitive fungal pathogens. In vitro tests on 114 ocular pathogenic fungal isolates exemplified the superiority of econazole to other available imidazoles. |
| Keywords: | econazole oculomycosis rabbits miconazole clotrimazole |
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