吸烟对成年男子红细胞免疫及其调节功能影响的实验研究

[目的]探讨吸烟对红细胞免疫及其调节功能的影响。[方法]将208名健康成年男子分成两组：吸烟组（152人）和对照组（56人），分别对其红细胞受体花环率（RBC－C3bRR)、红细胞免疫复合物花环率（RBC－ICR）、红细胞免疫增强因子（EF）及抑制因子（IF）进行测定。[结果]吸烟组的RBC－C3bRR、EF水平显著低于非吸烟对照组（P均＜0．01），而RBC－ICR、IF水平则显著高于非吸烟对照组（P均＜0．01）；相关分析表明RBC－C3bRR、EF水平与吸烟量及吸烟时间呈负相关，而RBC-ICF、IF水平则与吸烟量及吸烟时间呈正相关。[结论]吸烟可引起继发性免凤功能低下及降低红细胞免疫调节能力。

Experimental Study on Effects of Smoking on Immume and its Regulatory Function of Erythrocytes in Manhood

[Objective]To explore the impacts of smoking on immune and its regulatory function of erythrocytes[Methods]The forming rates of red blood cell C3b receptor rosette(RBC-C3bRR),red blood cell immunocomplex rosette(RBC-ICR),the enhancing activities of factor(EF) and inhibitory factor(IF) of erythrocytes were determined in 208 healthy adults,who were divided into smoking group(152 cases) and control group(56 cases)[Results]Significant lower forming rate of RBC-C3bRR and activity of EF,significant higher forming rate of RBC-ICR and IF activity were found in smoking group compared with non-smoking control group (P<001) The correlative analysis showed that,the forming rate of RBC-C3bRR and EF activity significantly negatively correlated with the amount and duration of smoking,but the forming rats of RBC-ICR and IF activity significantly positively correlated with the amount and duration of smoking[Conclusion]Smoking could secondarily deteriorate the immune function and immune regulatory function