五子汤治疗阴虚阳亢型高粘血症的临床观察

目的 :观察养阴药物五子汤治疗高粘血症的疗效。方法 :筛选辨证为阴虚阳亢型的高粘血症患者 10 1例 ,按其基础病分为高血压病组 ( 48例 )、冠心病组 ( 2 8例 )、糖尿病组 ( 2 5例 ) ,均以女贞子、枸杞子、桑椹子、决明子、葶苈子为主组方治疗。各组均于治疗前后查血液流变学指标 ,观察其变化 ,作自身对照。结果 :治疗后各组红细胞压积、全血粘度较治疗前有显著差异 ( P<0 .0 5～ 0 .0 1) ;而血浆粘度、纤维蛋白原及血沉无显著差异 ( P>0 .0 5 )。高血压病组、冠心病组、糖尿病组的总有效率分别为 91.6 %、 89.2 %、 84.0 %。结论 :五子汤能够对阴虚阳亢型高粘血症患者的全血粘度、红细胞压积等指标产生良性影响。

Therapeutic Observation of Wu Zi Tang in Treatment of Yin Xu Yang Kang Type Hyperviscosity

Objective: To study the therapeutic effects of the Yang Yin drugs, Wu Zi Tang, in treatment of hyperviscosity. Method: 101 patients were Yin Xu Yang Kang type hypervicosity, which included hypertension( n =48), Coronary disease( n =28), hyperglycemia( n =25). The drugs which were main composed of Nu Zhen Zi, Gou Qi ZI, Sang Sheng Zi, Jue Ming Zi, Ting Li Zi. The values of hemorheology were compared before and after treatment. Result: After treatment, the values of hematocrit and whole blood viscosity were significant difference in every groups( P < 0.05 ～ 0.01 ), but there were not significant difference in plasma viscosity, fibrinogen, and ESR( P > 0.05 ). The total efficiency in hypertension, coronary disease, hyperglycemia were 91.6% , 89.2% , 84.0% . Conclusion: Wu Zi Tang could result in good effect on hemorheology, it could be treated Yin Xu Yang Kang type hyperviscosity.