血清降钙素原及超敏C-反应蛋白在急性发热患者诊断中的应用

目的：探讨血清降钙素原（Procalcitonin，PCT）与超敏C-反应蛋白（hs—ClIP）检测在急性发热疾病病因学的诊断价值。方法：将我院120例发热待查患者做为研究对象，检测血清PCT和hs-CRP水平，并进行病原学检查确诊。评价PCT和hs—CRP对急性发热疾病病因学的诊断价值。结果：细菌感染组患者血清PCT和hs-CRP水平均显著高于非细菌感染组（P〈O．05）；PCT诊断细菌感染的敏感性、特异性、阳性预测值及阴性预测值分别为89．5％、82．4％、92．8％和75．7％，hs—CRP诊断细菌感染的敏感性、特异性、阳性预测值及阴性预测值分别为84．9％、58．8％、83．9％和60．O％。结论：细菌感染所致的急性发热患者血清PCT和hs—CRP水平显著升高，二者检测可用于急性发热患者的病因学诊断，PCT敏感性及特异性更好。

Application of Serum Procalcitonin and High Sensitive C-reactive Protein in Diagnosing Fever Patients

Objective： To explore the etiologic diagnostic value of procalcitonin （PCT） and high sensitive e-reactive protein （ hs-CRP） in diagnosis of fever patients. Method： 120 fever patients were selected as research subjects. Serum PCT and hs-CRP were detected and pathogenic examination were made to identify the disease. The diagnostic value of PCT and hs-CRP were evaluated. Result： Serum PCT and hs-CRP in bacteria infection patients were much higher than that of non-bacterial infection patients （ P〈0.05 ） ; The sensitivity, speeificityI positive predictive value and negative predictive value of PCT were 89.5%, 82.4%, 92.8% and 75.7% respectively, of which for hs-CRP were 84.9%, 58.8%, 83.9% and 60.0% respectively. Conclusion： Serum PCT and hs-CRP in the fever patients caused by bacteria infection greatly in- crease. The detection of PCT and hs-CRP can be used for etiologic diagnosis of fever patients. The sensitivity and speeificity of PCT are better than hs-CRP.