Indole derivatives |
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Authors: | N N Suvorov V N Buyanov |
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Institution: | (1) D. I. Mendeleev Moscow Chemicotechnological Institute, USSR |
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Abstract: | The reaction of -(indolyl-3)-alkyl bromides with sodium thiosulfate gave Bunte salts (sodium indolylalkyl thiosulfates) which were converted into disulfides by the action of alkali. These were reduced with lithium aluminum hydride to mercaptans which then were converted by the action of methyl iodide into sulfides and these into sulfonium salts. A chemotherapeutic investigation showed the Bunte salts to have weak tuberculo static activity.Translated from Khimiko-Farmatsevticheskii Zhurnal, No. 1, pp. 4–6, January, 1967. |
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