桥脑中央髓鞘溶解症的临床与MRI表现分析

目的　探讨桥脑中央髓鞘溶解症的临床表现及磁共振成像特点。方法　对我院经临床及影像学检查确诊的 1 1例桥脑中央髓鞘溶解症的MRI表现进行了回顾性分析。结果　临床表现有长期饮酒史者 7例 ,营养不良者 4例 ,出现低血钠者 1 0例 ;MRI均表现桥脑中央长T1 及长T2 信号 ,4例伴有皮层下白质及基底节病灶 ,3例病灶周边强化 ,2例病灶中央显著强化 ,4例不强化。结论　桥脑中央髓鞘溶解症MRI表现有一定特征性 ,结合临床表现及激素试验性治疗 ,可早期做出正确诊断。

An Analysis of the Clinical and MRI Features of Central Pontine Myelinolysis

Objective To study the clinical and MRI features of central pontine myelinolysis(CPM).Methods The MRI findings of 11 cases with central pontine myelinolysis verified by clinic and imagings were analyzed.Results There were history of drink wine long term in 7 cases,undernourishment in 4 cases,low-blood-sodium in 10 cases.Long T 1 and T 2 signal intensity was showed on MR in central pontine,focus presented under cortex cerebri and in nucleus basalis area in 4 cases.3 cases enhanced around focus,2 cases enhanced in center and 4 cases no enhanced on postcontrast MRI.Conclusion There are characteristic MRI features in central pontine myelinolysis,it is not difficult to diagnoses CPM in early stage if its clinical manifestations and testing treatment with hormone is associated with MRI features.