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| 谷氨酰胺强化的TPN在大肠癌患者术后的应用 | |
| 引用本文： | 李航宇,苏东明,许元鸿,郭仁宣,张菁茹,朱广军.谷氨酰胺强化的TPN在大肠癌患者术后的应用[J].临床医药实践,2002,11(9):653-655. |
| 作者姓名： | 李航宇 苏东明 许元鸿 郭仁宣 张菁茹 朱广军 |
| 作者单位： | 1. 中国医科大学附属一院,辽宁,沈阳,110001 2. 辽宁省肿瘤医院.辽宁沈阳,110001 3. 盘锦市第二人民医院,辽宁,盘锦,124000 |
| 摘 要： | 目的 :探讨谷氨酰胺 ( Gln)强化的肠外营养 ( TPN )对大肠癌术后患者的作用。方法 :4 0例大肠癌患者随机分为实验组 ( TPN+ Gln)和对照组 (常规 TPN) ,观察氮平衡、血浆白蛋白水平、术后疲劳评分等各项指标的变化。结果 :对照组的术后平均住院时间为 ( 13.12± 3.2 1) d,而实验组为 ( 10 .90± 2 .81) d,两者比较有显著性差异 ( P<0 .0 5) ;两组患者术前血浆白蛋白水平相似 ,在术后第 8天实验组白蛋白水平普遍高于对照组 ,但两者之间无统计学差异 ;术后8d实验组氮平衡明显改善 ,与对照组相比差异显著 ( P<0 .0 1) ;术后第 8天实验组患者主观感觉好于对照组 ( P<0 .0 5)。结论 :大肠癌患者术后予以 Gln强化的 TPN支持 ,比常规 TPN更有利于术后负氮平衡的改善及血浆白蛋白的恢复 ,缩短住院时间、减少术后并发症 ,并能显著改善术后疲劳 |
| 关 键 词： | 大肠癌 谷氨酰胺 肠外营养 |
| 文章编号： | 1006-8716(2002)09-0653-03 |
| 修稿时间： | 2002年7月11日 |
Effect of glutamine-intensified total parenteral nutrition on the postoperative patients with colorectal carcinoma |
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| Abstract: | Objective:To investigate the effect of glutamine-intensified TPN in the postoperative patients with colorectal carcinoma.Methods:40 patients were divided into two groups including study group(TPN+G1n) and control group(standard TPN).Nitrogen balance,serum albumin and score of postoperative fatigue were tested.Results:Average postoperative stay of study group shortened significantly as caompared with control group( P <0.05).Serum ablumin levels of study group was higher than control group,but there was no significantly difference.Nitrogen balance was better in study group at the 8th postoperative day ( P <0.01).Score of postoperative fatigue was better in study group at the 8th postoperative day ( P <0.05).Conclusions:The treatment of glutamine-intensified TPN can improve the effect of parenteral nutrition on the patients with colorectal carcinoma. |
| Keywords: | colorectal carcinoma glutamine total parenteral nutrition |
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