| 木丹颗粒对2型糖尿病患者颈动脉内膜中层厚度及血浆炎症因子水平的影响 |
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| 引用本文： | 施剑,伊桐凝,于世家.木丹颗粒对2型糖尿病患者颈动脉内膜中层厚度及血浆炎症因子水平的影响[J].光明中医,2012,27(5):896-897. |
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| 作者姓名： | 施剑 伊桐凝 于世家 |
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| 作者单位： | 辽宁中医药大学附属医院内分泌科,沈阳,110032 |
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| 摘 要： | 目的观察木丹颗粒对2型糖尿病(T2DM)患者颈动脉内膜中层厚度及血浆炎症因子(C-RP)水平的影响。方法将符合2型糖尿病诊断标准的67例患者随机分为两组,两组控制血糖基础治疗相同,中药组配合中药木丹颗粒。结果①中药组治疗后FPG,2hPG,血脂TC、TG,LDL-C、BMI水平均下降,但没有统计学意义,而HDL-C则升高,亦没有统计学意义;②T2DM组的C-RP水平、IMT均高于中药组(P<0.05)。结论木丹颗粒通过减轻血管炎症反应,减缓动脉硬化的进程,从而可以延缓糖尿病大血管并发症发生及发展。
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| 关 键 词： | 木丹颗粒 2型糖尿病 颈动脉内膜 炎症因子 |
The Effect of Mudangranules on Carotid Intimamedia Thickness and Inflammatory Factor Type 2 Diabetes Mellitus |
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| Shi Jian
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Yi Tongning
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Yu Shiiia.The Effect of Mudangranules on Carotid Intimamedia Thickness and Inflammatory Factor Type 2 Diabetes Mellitus[J].Journal of Traditional Chinese Medicine,2012,27(5):896-897. |
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| Authors: | Shi Jian Yi Tongning Yu Shiiia |
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| Institution: | Shi Jian Yi Tongning Yu Shijia(Endocrinology department of affiliated hospital of Liaoning TCM university,Shenyang 110032) |
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| Abstract: | Objective To investigate the effect of Mudangranules on carotid intimamedia thickness(CIMT) and C reactive protein(CRP) in type 2 diabetes mellitus(T2DM).Methods A total of 67 T2DM were randomly divided into twogroups after their bloodglucose reach normal standard with western medicine.Onegroup was continue the original treatment,and the other was added Mudangranules for anther 4 weeks.Result The level of CRP and CIMT in western medicinegroup were higher significantly than those of MUDANgroup(P<0.05).While the level of HDL-C was increase and TC、TG,LDL-C and BMI were decline of Mudangroups with no significant difference compared with western medicine(P>0.05).Conclusion Mudangranules can delay the occurrence and development of macrovascular complications of diabetes by reducing blood vessel inflammation and dallying the process of atherosclerosis. |
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| Keywords: | Mudangranules type 2 diabetes mellitus carotid intimamedia thickness inflammatory factor |
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