| 异常咬合对成年大鼠颞颌关节影响的初步研究 |
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| 引用本文： | 徐晓梅,税桦桦,黄丽,罗玲,杨四维. 异常咬合对成年大鼠颞颌关节影响的初步研究[J]. 泸州医学院学报, 2010, 33(2): 133-137 |
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| 作者姓名： | 徐晓梅 税桦桦 黄丽 罗玲 杨四维 |
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| 作者单位： | 1. 泸州医学院附属口腔医院正畸科,四川,泸州,646000
2. 第三军医大学附属西南医院口腔科 |
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| 摘 要： | 目的：探讨异常咬合关系对成年大鼠颞下颌关节的影响。方法：选用19周龄雄性Wistar大鼠50只作为研究对象,按实验目的将大鼠随机分为实验组（30只）、操作对照组（10只）和空白对照组（10只）。应用螺旋拉簧以60g力作用于实验组大鼠的上颌第一磨牙,使其近中移动,形成异常咬合关系。加力后2周、3周、4周、5周、6周分别处死6只实验组大鼠,2只操作对照组大鼠和2只空白对照组大鼠。取其颞下颌关节做HE染色、Masson染色,观测髁状突的变化。结果：1.实验组髁状突纤维层表层的胶原纤维间水肿,组织松解,形成细小的裂隙;胶原纤维从表面剥离;肥大层变薄;初期骨小梁出现轻度的排列紊乱,其后骨小梁排列趋于恢复;2.髁状突软骨厚度变化：实验组可见髁状突软骨厚度下降,由后向前依次变薄。前带厚度随时间变化不明显,后带的变化程度最大;3.Masson染色结果：在实验组中髁状突软骨和软骨下骨出现红染增加。结论：异常咬合将导致大鼠颞下颌关节出现退行性变,主要表现为髁状突软骨变薄和纤维层的轻度破坏。
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| 关 键 词： | 颞下颌关节改建 异常咬合 髁突软骨厚度 成人正畸治疗 |
THE PRELIMINARY STUDY OF THE EFFECT OF EXPERIMENTAL ABNORMAL OCCLUSION ON TEMPOROMANDIBULAR JOINT IN ADULT RATS |
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| Xu Xiaomei,et al Orthodontic Department,the Stomatological Hospital of Luzhou Medical College. THE PRELIMINARY STUDY OF THE EFFECT OF EXPERIMENTAL ABNORMAL OCCLUSION ON TEMPOROMANDIBULAR JOINT IN ADULT RATS[J]. Journal of Luzhou Medical College, 2010, 33(2): 133-137 |
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| Authors: | Xu Xiaomei et al Orthodontic Department the Stomatological Hospital of Luzhou Medical College |
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| Affiliation: | Xu Xiaomei,et al Orthodontic Department,the Stomatological Hospital of Luzhou Medical College |
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| Abstract: | Objective:To investigate the effect of abnarmal occlusion on the temporomandibular joint in adult rats.Methods:In this experiment,50 Wistar male rats (19 weeks) were randomly divided into three groups:occlusion change group(n=30),sham control group(n=10)and blank control group(n=10).The maxillary first molars of the test group were moved mesially by coil spring (60g) and uncoordinated cusp-fossa occlusion contact relationship was established.6 rats in occlusion change group,2 rats in sham control group and ... |
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| Keywords: | Temporomandibular joint remodeling Abnormal occlusion Thickness of condylar cartilage Adult orthodontic treatment |
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