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阿尔茨海默病患者微量元素检测分析
引用本文:刘秀夫,寇盛斌,傅力文,李丽秋,郭丽英,彭小华.阿尔茨海默病患者微量元素检测分析[J].中华神经医学杂志,2009,8(9).
作者姓名:刘秀夫  寇盛斌  傅力文  李丽秋  郭丽英  彭小华
作者单位:1. 深圳市社会福利中心康复医院,518049
2. 南方医科大学球江医院神经外科,广州,510282
3. 深圳市社会福利中心老人颐养院,518049
摘    要:目的 探讨微量元素与阿尔茨海默病(AD)的临床关系,为AD的防治提供依据.方法对深圳市社会福利中心老人颐养院2006年1月至2008年9月收治36例AD患者和46例对照者进行头发的锌、铁、铜、锰、铅5种微量元素及钙元素的检测,对数据进行统计学处理. 结果 AD组患者头发的锌、钙、锰含量均低于对照组,差异有统计学意义(P<0.05). 结论 AD病理与锌、钙、锰等微量元素的含量低下有密切关系.

关 键 词:阿尔茨海默病  微量元素      

Analysis of the trace elements in the hair of elderly patients with Alzheimer's disease
LIU Xiu-fu,KOU Sheng-bin,FU Li-weng,LI Li-qiu,GUO Li-ying,PENG Xiao-hua.Analysis of the trace elements in the hair of elderly patients with Alzheimer's disease[J].Chinese Journal of Neuromedicine,2009,8(9).
Authors:LIU Xiu-fu  KOU Sheng-bin  FU Li-weng  LI Li-qiu  GUO Li-ying  PENG Xiao-hua
Abstract:Objective To investigate the association between the trace elements and senile dementia.Methods The trace elements including zinc,iron,copper,manganese,and lead elements and calcium in the hair of the elderly patients with Alzheimer' s disease(AD)admitted in our hospital from January,2006 to September,2008 were analyzed,and the results were compared with those from 46 control subjects.Results Zinc,calcium and manganese levels in the AD group were significantly lower than those in the control group(P<0.05).Conclusion Lowered contents of the trace elements zinc,calcium and manganese might be associated with the pathology of AD.
Keywords:Alzheimer's disease  Senile dementia  Zinc  Calcium  Manganese
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