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Characteristics of developmentally early alcohol use disorder symptom reports: A prospective-longitudinal community study
Authors:S Behrendt  G Bühringer  A Perkonigg  R Lieb  K Beesdo-Baum
Institution:1. Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Chemnitzer Str. 46, D-01187 Dresden, Germany;2. University of Basel, Department of Psychology, Division of Clinical Psychology and Epidemiology, Missionsstrasse 60-62, 4055 Basel, Switzerland;3. Max Planck Institute of Psychiatry, Kraepelinstr. 2-10, D-80804 Munich, Germany;4. IFT Institut fuer Therapieforschung, Parzivalstraße 25, D-80804 Munich, Germany;5. University of Zurich, Department of Psychology, Division of Psychopathology and Clinical Intervention, Binzmühlestr. 14/17, CH-8050 Zurich, Switzerland
Abstract:

Background

There is little prospective-epidemiological information on symptoms of DSM-IV-alcohol use disorder (alcohol abuse and dependence; AUD) that may be typical for early AUD stages or the developmental periods of adolescence and early adulthood.

Aims

To investigate AUD symptoms (AUDS) cross-sectionally at three subsequent assessment waves regarding prevalence rates, symptom counts, associated drinking patterns, positive predictive values (PPV) for DSM-IV-alcohol dependence (AD), and AUDS stability over time.

Methods

N = 2039 community subjects (baseline age 14–24 years) participated in a baseline and two follow-up assessment(s) over up to ten years. DSM-IV-AUDS, DSM-IV-AUD and craving were assessed with the DSM-IV/M-CIDI.

Results

Over the assessment waves, tolerance and much time were most and role obligations and withdrawal least frequent. Most subjects with DSM-IV-AUDS reported only one symptom (47.2–55.1%). PPV for DSM-IV-AD only exceeded 70% for activities, problem, withdrawal, and desired control; PPV were lowest for tolerance and hazardous use. For most AUDS, AUDS report compared to non-report was associated with elevated drinking frequency and amounts. Stability of baseline AUDS at four-year and ten-year follow-up did not exceed 36.4% for any symptom.

Conclusions

The overall pattern of most/least frequent AUDS reported in adolescence and early adulthood resembles findings in older adults and does not suggest a developmentally specific symptom pattern. Moderate AUDS-stability and considerable remission rates indicate that AUDS in this age group are transient for a considerable proportion of subjects. However, the associations with elevated consumption indicate that AUDS reports early in life need to be taken seriously in prevention and intervention.
Keywords:DSM-IV alcohol use disorder  Alcohol abuse  Alcohol dependence  Symptoms  Adolescence  Longitudinal  Epidemiology
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