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恶性疟血涂片见大滋养体1例
引用本文:王用斌,孔祥礼,许艳,张颖,李瑾,赵长磊,缪峰,陈锡欣,黄炳成. 恶性疟血涂片见大滋养体1例[J]. 中国血吸虫病防治杂志, 2014, 26(3): 355-356
作者姓名:王用斌  孔祥礼  许艳  张颖  李瑾  赵长磊  缪峰  陈锡欣  黄炳成
作者单位:1山东省医学科学院, 山东省寄生虫病防治研究所 (济宁 272033); 2济南大学?山东省医学科学院医学与生命科学学院; 3山东省日照市疾病预防控制中心
基金项目:中国全球基金疟疾项目实施性研究专项基金(201201055)(感谢中国疾病预防控制中心寄生虫病预防控制所李美博士在标本基因检测方面给予的帮助!)
摘    要:本文报告1例非洲输入性非典型恶性疟病例, 其血涂片显微镜下可见较多大滋养体期原虫, 部分虫体可见棕黄色色素颗粒, 呈点状或团块状, 虫体形态与间日疟原虫、 卵形疟原虫相似, 经PCR基因检测确诊为恶性疟。非重症恶性疟病例外周血中出现大滋养体期原虫较为罕见, 镜检时应注意与其他疟原虫鉴别。

关 键 词:恶性疟原虫; 非典型; 大滋养体; 巢式PCR; 鉴别  

Large trophozoites in blood smear of falciparum malaria: one case report
WANG Yongbin,KONG Xiangli,XU Yan,ZHANG Ying,LI Jin,ZHAO Changlei,MIAO Feng,CHEN Xixin,HUANG Bingcheng. Large trophozoites in blood smear of falciparum malaria: one case report[J]. Chinese journal of schistosomiasis control, 2014, 26(3): 355-356
Authors:WANG Yongbin  KONG Xiangli  XU Yan  ZHANG Ying  LI Jin  ZHAO Changlei  MIAO Feng  CHEN Xixin  HUANG Bingcheng
Affiliation:1 Shandong Academy of Medical Sciences| Shandong Institute of Parasitic Diseases| Shandong Province|Jining 272033|China;2School of Medicine and Life Sciences|University of Jinan?Shandong Academy of Medical Sciences|China;3 Rizhao Center for Dis?ease Control and Prevention|Shandong Province|China
Abstract:This paper reports one case of atypical falciparum malaria imported from Africa,whose blood smear contains many large trophozoites,with punctiform or massive brown pigment granules,the body shape of the plasmodium is similar to that of Plas-modium vivax and Plasmodium ovale. After the gene detection by PCR,the case was diagnosed as falciparum malaria. As large tro-phozoites were rarely seen in the peripheral blood of non-severe falciparum malaria cases,much attention should be paid to the identification of Plasmodium falciparum and other plasmodia in microscopic examinations.
Keywords:Plasmodium falciparum;Atypical; Large trophozoite;Nested PCR; Identification
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