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异常妊娠结局妇女弓形虫感染状况
引用本文:张淑芳,宋任浩. 异常妊娠结局妇女弓形虫感染状况[J]. 中国血吸虫病防治杂志, 2014, 26(4): 437
作者姓名:张淑芳  宋任浩
作者单位:1河北省廊坊市第四人民医院产科 (廊坊065700);2 河北省血液中心检验科
摘    要:目的 目的 探讨弓形虫感染与异常妊娠结局的关系。方法 方法 选择2013年3-12月廊坊市第四人民医院妇产科就诊的126例异常妊娠结局妇女为实验组, 本地区263例正常妊娠育龄妇女为对照组, 采用酶联免疫吸附试验进行弓形虫IgM、 IgG抗体检测, 对两组数据进行处理和分析。结果 结果 异常妊娠结局妇女弓形虫IgM、 IgG阳性率分别为7.94%和19.84%, 对照组阳性率分别为1.90%和8.75%,两组差异均有统计学意义 (χ2IgM =6.82、χ2IgG =9.70, P均<0.01); 对照组弓形虫IgM、 IgG阳性率明显低于各异常妊娠结局组, 差异均有统计学意义(χ2自然流产 =10.40、χ2早产 =9.03、χ2胎停 =4.32、χ2出生缺陷 =4.04, P均<0.05)。4种异常妊娠结局妇女弓形虫IgM、 IgG阳性率差异均无统计学意义 (P均>0.05)。结论 结论 弓形虫感染可致严重异常妊娠结局, 应采取综合措施预防孕妇弓形虫感染。

关 键 词:弓形虫; 异常妊娠; IgM抗体; IgG抗体  

Toxoplasma gondii infection status in abnormal pregnancy women
ZHANG Shu-Fang,SONG Ren-Hao. Toxoplasma gondii infection status in abnormal pregnancy women[J]. Chinese journal of schistosomiasis control, 2014, 26(4): 437
Authors:ZHANG Shu-Fang  SONG Ren-Hao
Affiliation:1 Obstetrical Department|Fourth People’ s Hospital of Langfang|Hebei Province|Langfang 065700|China;2 Clinical Labora?tory| Hebei Blood Center| Hebei Province| China
Abstract:Objective Objective To investigate the relationship between Toxoplasma gondii(TOX)infection and abnormal pregnancyoutcomes. Methods Methods A total of 126 cases of abnormal pregnancy women in the Department of Obstetrics and Gynecology,theFourth People’ s Hospital of Langfang from March to December 2013 were chosen as an experimental group,and 263 cases ofnormal pregnancy women of childbearing age as a control group. The TOX?IgM and ?IgG antibodies were detected by ELISA. Thedata in the two groups were processed and analyzed by SPSS13.0. Results Results The positive rates of TOX?IgM,?IgG in 126 cases ofabnormal pregnancy women were 7.94% and 19.84% respectively,and 1.90% and 8.75% in the control group respectively,andthere were significant differences between them(χ2IgM = 6.82,χ2IgG = 9.70,both P<0.01) . The positive rates of TOX?IgM,?IgGin the normal pregnancy women were lower than those in 4 sub?groups of abnormal pregnancy women,and all the differenceswere statistically significant( χ2spontaneous abortion = 10.40,χ2premature delivery = 9.03,χ2embryo damage =4.32,χ2birth defect = 4.04,all P<0.05) . However,the TOX?IgM,?IgG positive rates in the 4 sub?groups of abnormal pregnancy women had no statistically signifi?cant difference(P > 0.05) . Conclusions Conclusions TOX infection could cause serious abnormal pregnancy outcomes. Therefore,thecomprehensive control measures should be strengthened.
Keywords:Toxoplasma gondii;Abnormal pregnancy;IgM antibody; IgG antibody
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