| 关节镜下保留残端重建前交叉韧带与不保留残端重建的Meta分析 |
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| 引用本文： | 张 磊,谢崇新,白靖平. 关节镜下保留残端重建前交叉韧带与不保留残端重建的Meta分析[J]. 中国组织工程研究, 2016, 20(20): 3032-3040. DOI: 10.3969/j.issn.2095-4344.2016.20.019 |
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| 作者姓名： | 张 磊 谢崇新 白靖平 |
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| 作者单位： | 1新疆医科大学附属肿瘤医院骨与软组织科，新疆维吾尔自治区乌鲁木齐市 830011；2武警兵团指挥部医院外一科，新疆维吾尔自治区乌鲁木齐市 830002 |
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| 基金项目： | 新疆生产建设兵团自然科学基金(2015AD004) |
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| 摘 要： | BACKGROUND: There are controversies about preserving the remnant in the anterior cruciate ligament reconstruction procedure because of its uncertain therapeutic effects. OBJECTIVE:To compare the efficacy and safety of preserving-remnant with removing-remnant for arthroscopic anterior cruciate ligament reconstruction using a meta-analysis.METHODS: A computer-based online search was conducted in PubMed, Embase, the Cochrane Library, CDSR, CBM, and CNKI databases by using the English key words of “anterior cruciate ligament AND remnant (OR stump) AND randomized controlled trial (RCT) OR quasi-RCT” and the Chinese key words of “anterior cruciate ligament reconstruction, preserving-remnant, removing-remnant” to screen the relevant articles published from 1995 to July 2015. Meta-analysis was performed using Review Manager 5.3 software.RESULTS AND CONCLUSION:A total of 13 randomized controlled trials were included. The meta-analysis results showed that there were no statistically significant differences in KT1000/2000 scores (OR=-0.28, 95%CI: -0.76-0.20, P=0.25), the good rate of synoveal coverage (OR =-0.30, 95%CI: -0.30-0.90, P=0.32), and the incidence of cyclops leions (OR=0.87, 95%CI: 0.63-2.90, P=0.44). Postoperative Lysholm scores (OR=2.45, 95%CI: 0.52-4.39, P=0.01), proprioceptive function (OR=-1.72, 95%CI: -3.32 to 0.13, P=0.03), tunnel enlargement (OR=-0.66, 95%CI: -1.08 to -0.23, P=0.002) in preserving-remnant were superior to removing-remnant for arthroscopic anterior cruciate ligament reconstruction. These results suggest that both preserving-remnant and removing-remnant for arthroscopic anterior cruciate ligament reconstruction can obtain satisfactory antero-posterior stability of the knee. Preserving-remnant exhibits superiority in post-operative scores of the knee, proprioceptive function, tunnel enlargement. Further high-quality randomized controlled trials are warranted because of some low-quality studies and the existing biases.中国组织工程研究杂志出版内容重点：组织构建；骨细胞；软骨细胞；细胞培养；成纤维细胞；血管内皮细胞；骨质疏松；组织工程
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| 关 键 词： | 组织构建 组织工程 肌肉肌腱韧带 前交叉韧带 保留残端 不保留残端 重建 随机对照 本体感觉 Cyclops病变 骨道扩大 膝关节稳定性 Meta分析 |
Preserving-remnant versus removing-remnant for arthroscopic anterior cruciate ligament reconstruction: a Meta-analysis |
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| Zhang Lei,Xie Chong-xin,Bai Jing-ping. Preserving-remnant versus removing-remnant for arthroscopic anterior cruciate ligament reconstruction: a Meta-analysis[J]. Chinese Journal of Tissue Engineering Research, 2016, 20(20): 3032-3040. DOI: 10.3969/j.issn.2095-4344.2016.20.019 |
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| Authors: | Zhang Lei Xie Chong-xin Bai Jing-ping |
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| Affiliation: | 1Deparment of Bone and Soft Tissue, Affiliated Tumor Hospital, Xinjiang Medical University, Urumqi 830011, Xinjiang Uyghur Autonomous Region, China; 2the First Department of Surgery, Hospital Affiliated to Xinjiang Production and Construction Corps Headquarters of Chinese People’s Armed Police Forces, Urumqi 830002, Xinjiang Uyghur Autonomous Region, China |
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| Abstract: | |
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| Keywords: | Tissue Engineering Anterior Cruciate Ligament Meta-Analysis |
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