股骨颈骨折修复后股骨头坏死7个相关因素：199例回顾分析

BACKGROUND: The incidence of femoral head necrosis after internal fixation in femoral neck fracture is at high level, but the risk factors are still under discussion. OBJECTIVE:To retrospectively propose and analyze the relative risk factors of femoral head necrosis after internal fixation with femoral neck fracture in patients younger than 60 years old. METHODS:Data from 199 patients with femoral neck fractures, younger than 60 years, undergoing closed reduction and internal fixation were analyzed retrospectively. Seven factors including age, sex, body mass index, Garden classification, fracture seasons, reduction quality and weight-bearing time after internal fixation were statistically analyzed to evaluate their correlation with femoral head necrosis.RESULTS AND CONCLUSION: The incidence of femoral head necrosis was 13.1% among the 199 cases. Body mass index, Garden classification, fracture seasons, reduction quality were significantly associated with femoral head necrosis. The age, sex and weight-bearing time were in significantly associated with femoral head necrosis. In multivariate logistic regression analysis, Garden classification, reduction quality and fracture seasons (winter versus summer) had overt effects on development of femoral head necrosis. These results suggest that Garden classification and reduction quality make an important effect on the healing of femoral neck fracture. In addition, fracture in winter may be the risk factor of the femoral head necrosis after internal fixation in femoral neck fracture.|中国组织工程研究杂志出版内容重点：组织构建；骨细胞；软骨细胞；细胞培养；成纤维细胞；血管内皮细胞；骨质疏松；组织工程

Seven risk factors of femoral head necrosis after internal fixation in femoral neck fractures: a retrospective analysis of 199 cases