2014年北京市昌平区疑似预防接种异常反应监测分析

摘要:目的 掌握2014年北京市昌平区疑似预防接种异常反应(Adverse Events Following Immunization,AEFI)的发生情况。方法 通过分析2014年昌平区AEFI报告数据,采用相关指标描述AEFI报告情况。结果 2014年昌平区报告AEFI共222例,AEFI报告率为20.73/10万。全区17个行政区均有报告,回龙观报告例数最多共50例。发病年龄集中在2岁以下,多在接种后1天内发生。124例临床表现为发热/红肿/硬结,219例痊愈。报告病例涉及21种生物制品,其中吸附无细胞百白破联合疫苗(DTaP)发生AEFI报告例数居首位(79例),7价肺炎疫苗(PCV-7)AEFI发生报告率居首位(94.16/10万)。结论 2014年昌平区AEFI监测报告率较高,发生年龄小,发生时间间隔短、症状轻。涉及21类生物制品,其中(DTaP)报告病例最多,(PCV-7)发生报告率最高。

Adverse events following immunization in Changping district,Beijing,2014

Abstract:Objective To comprehend the adverse events following immunization(AEFI)in Changping district of Beijing in 2014.Methods We described the epidemiological trends with relevant incidence by analyzing the data of AEFI in Beijing during 2014.Results A total of 222 AEFI were reported.The incidence was 20.73/100000.The cases were reported by 17 attached regions of Changping.Most cases were reported by Huilongguan(50 cases).Children under 2 years old were the highest risk group.Most cases happened one day after the vaccination.124 cases were diagnosed as fever/swelling /induration while 219 cases were fully recovered.21 kinds of vaccines were involved,diphtheria-tetanus-acellular-pertussis vaccine(DTaP)caused the highest number of cases(79 cases),Pneumococcal 7-valent conjugate vaccine(PCV-7)caused the highest incidence of cases(94.16/100000).Conclusion The incidence of AEFI in Changping during 2014 is higher than those in the other year,with the characteristics of young age,short time interval and mild symptom.Among the involved 21 kinds of vaccines,DTaP caused the highest number of cases,PCV-7 caused the highest incidence of cases.