首页 | 本学科首页   官方微博 | 高级检索  
     

3D打印个体化模板联合CT引导125I粒子植入治疗恶性肿瘤质量评价
引用本文:张颖,林琦,袁苑,戴建建,耿宝成,徐瑞彩,刘亚坤,韩明勇. 3D打印个体化模板联合CT引导125I粒子植入治疗恶性肿瘤质量评价[J]. 山东大学学报(医学版), 2016, 54(11): 44-50. DOI: 10.6040/j.issn.1671-7554.0.2016.1157
作者姓名:张颖  林琦  袁苑  戴建建  耿宝成  徐瑞彩  刘亚坤  韩明勇
作者单位:山东大学附属省立医院东院保健综合(肿瘤)科, 山东 济南 250014
基金项目:国家自然科学基金(81272351)
摘    要:目的 对3D打印个体化模板联合CT引导125I粒子植入术后验证的剂量学参数进行评价,探讨其治疗肿瘤的可行性。 方法 收集2015年12月至2016年7月住院患者30例,全部患者术前行CT模拟定位,设计并应用3D打印机打印个体化模板。手术时,将患者进行复位、模板与体表术区对合、按术前计划进针、植入粒子,术后即刻行CT扫描,进行剂量学验证。按照英国哥伦比亚癌症研究中心粒子植入质量评价标准对植入质量进行评价。 结果 30例患者均成功设计并打印个体化模板。28例技术成功,其中22例患者术后实际植入粒子数与术前计划一致,另外6例给予术中优化。术后验证评价结果,优:14例;良:10例;中:4例;差:0例。2例技术失败。 结论 3D 打印个体化模板联合CT引导粒子植入治疗恶性肿瘤能够保证粒子植入质量控制的实施,值得临床推广应用。

关 键 词:个体化模板  125I粒子  3D打印  恶性肿瘤  
收稿时间:2016-09-13

Feasibility of 3D print individual template combined with CT-guided 125I seed implantation for malignant tumors
ZHANG Ying,LIN Qi,YUAN Yuan,DAI Jianjian,GENG Baocheng,XU Ruicai,LIU Yakun,HAN Mingyong. Feasibility of 3D print individual template combined with CT-guided 125I seed implantation for malignant tumors[J]. Journal of Shandong University:Health Sciences, 2016, 54(11): 44-50. DOI: 10.6040/j.issn.1671-7554.0.2016.1157
Authors:ZHANG Ying  LIN Qi  YUAN Yuan  DAI Jianjian  GENG Baocheng  XU Ruicai  LIU Yakun  HAN Mingyong
Affiliation:Department of Health Oncology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan 250014, Shandong, China
Abstract:Objective To evaluate the feasibility of 3D print individual template and CT-guided 125I seed implantation for malignant tumors. Methods A total of 30 patients were involved in this study. Before 125I seed implantation, the patients received CT simulation orientation as the predicted posture. The individual template was designed by the brachytherapy treatment planning system(BTPS), and printed by 3D print technique. Every patient received 125I seed implantation under the guidance of 3D print individual template and CT scan. After implantation, treatment quality was evaluated with CT and BTPS. Results The 3D print individual templates were successfully designed and manufactured. Of all 30 cases, 28 were successfully implanted with the 3D print templates, and 2 failed. Of the 28 successful cases, 22 had the same number of seeds implanted as scheduled before operation, and the other 6 cases optimized the number of seeds during operation. Postoperative evaluation indicated that 14(50.0%)cases had excellent implants, 10(35.7%)had good implants, 4(14.3%)had suboptimal implants, and no case had poor implants. Conclusion The 3D print individual template and CT-guided 125I seed implantation appears to be a feasible, safe and effective modality for the treatment of malignant tumors.
Keywords:Malignancy  3D print  Individual template  125I seed  
点击此处可从《山东大学学报(医学版)》浏览原始摘要信息
点击此处可从《山东大学学报(医学版)》下载全文
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号